Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 8/20 | 0.57 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.55 |
| ▸ | CTSS | P25774 | 2/20 | 0.54 |
| ▸ | CTSB | P07858 | 2/20 | 0.54 |
| ▸ | CTSL | P07711 | 1/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29480470 | 0.91 | CTSK (0.57) | CTSKPTPN1CTSSCTSBCTSL | |
| SCHEMBL29385108 | 0.89 | PTPN1 (0.56) | CTSKPTPN1CTSBHDAC1HDAC2 | |
| SCHEMBL30844624 | 0.88 | HDAC1 (0.51) | CTSKPTPN1HDAC1HDAC2 | |
| SCHEMBL13402442 | 0.87 | HDAC1 (0.54) | HDAC1HDAC2 | |
| SCHEMBL28527138 | 0.87 | HDAC1 (0.54) | HDAC1HDAC2 | |
| SCHEMBL31000548 | 0.87 | HDAC1 (0.54) | HDAC1HDAC2 | |
| SCHEMBL11912033 | 0.87 | HDAC1 (0.54) | HDAC1HDAC2 | |
| SCHEMBL29397673 | 0.87 | HDAC1 (0.54) | HDAC1HDAC2 | |
| SCHEMBL9449334 | 0.87 | PTPN1 (0.49) | PTPN1 | |
| N- (9-Fluorenylmethoxycarbonyl)-L-Leucine SCHEMBL120560 | 0.87 | MDM4 (0.58) | PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0531443-A4 | METHODS FOR TREATING INFLAMMATION AND COMPOUNDS AND COMPOSITIONS SUITABLE FOR USE THEREIN | — | 1993-04-21 | — | — | EP | disclosed |
| EP-0531443-A1 | METHODS FOR TREATING INFLAMMATION AND COMPOUNDS AND COMPOSITIONS SUITABLE FOR USE THEREIN | NOVA PHARMACEUTICAL CORPORATION (US) | 1993-03-17 | — | — | EP | disclosed |
| WO-1991018596-A1 | METHODS FOR TREATING INFLAMMATION AND COMPOUNDS AND COMPOSITIONS SUITABLE FOR USE THEREIN | WEITZBERG MOSHE (US) | 1991-12-12 | — | — | WO | disclosed |