Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.54 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.54 |
| ▸ | IDO1 | P14902 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MDM4 | O15151 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | TNF | P01375 | 1/20 | 0.49 |
| ▸ | CASP3 | P42574 | 2/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.48 |
| ▸ | TDO2 | P48775 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13402442 | 1.00 | HDAC1 (0.54) | HDAC1HDAC2IDO1KMT2AMDM4 | |
| SCHEMBL29397673 | 1.00 | HDAC1 (0.54) | HDAC1HDAC2IDO1KMT2AMDM4 | |
| SCHEMBL11912033 | 1.00 | HDAC1 (0.54) | HDAC1HDAC2IDO1KMT2AMDM4 | |
| SCHEMBL31000548 | 1.00 | HDAC1 (0.54) | HDAC1HDAC2IDO1KMT2AMDM4 | |
| SCHEMBL29555721 | 0.91 | HDAC1 (0.57) | HDAC1HDAC2IDO1KMT2AMDM4 | |
| SCHEMBL377964 | 0.91 | HDAC1 (0.57) | HDAC1HDAC2IDO1KMT2AMDM4 | |
| SCHEMBL392598 | 0.91 | HDAC1 (0.57) | HDAC1HDAC2IDO1KMT2AMDM4 | |
| SCHEMBL15982313 | 0.91 | HDAC1 (0.57) | HDAC1HDAC2IDO1KMT2AMDM4 | |
| SCHEMBL16167663 | 0.90 | CTSK (0.47) | HDAC1HDAC2IDO1KMT2ATNF | |
| SCHEMBL18718108 | 0.90 | CASP3 (0.51) | HDAC1HDAC2IDO1KMT2AMDM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112479933-A | Preparation method of N-fluorenylmethoxycarbonyl-3-chloro-alanine benzyl ester | 吉尔生化（上海）有限公司 | 2021-03-12 | — | — | CN | disclosed |