SCHEMBL29397673

SCHEMBL29397673

O=C(N[C@@H](CO)C(=O)OCc1ccccc1)OCC1c2ccccc2-c2ccccc21

nearest known ligand 0.60

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ HDAC1 Q13547 1/20 0.54
▸ HDAC2 Q92769 1/20 0.54
▸ IDO1 P14902 2/20 0.53
▸ KMT2A Q03164 2/20 0.51
▸ MDM4 O15151 2/20 0.51
▸ TP53 P04637 2/20 0.51
▸ TNF P01375 1/20 0.49
▸ CASP3 P42574 2/20 0.48
▸ EPHX2 P34913 1/20 0.48
▸ TDO2 P48775 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13402442 1.00 HDAC1 (0.54) HDAC1HDAC2IDO1KMT2AMDM4
SCHEMBL28527138 1.00 HDAC1 (0.54) HDAC1HDAC2IDO1KMT2AMDM4
SCHEMBL11912033 1.00 HDAC1 (0.54) HDAC1HDAC2IDO1KMT2AMDM4
SCHEMBL31000548 1.00 HDAC1 (0.54) HDAC1HDAC2IDO1KMT2AMDM4
SCHEMBL29555721 0.91 HDAC1 (0.57) HDAC1HDAC2IDO1KMT2AMDM4
SCHEMBL377964 0.91 HDAC1 (0.57) HDAC1HDAC2IDO1KMT2AMDM4
SCHEMBL392598 0.91 HDAC1 (0.57) HDAC1HDAC2IDO1KMT2AMDM4
SCHEMBL15982313 0.91 HDAC1 (0.57) HDAC1HDAC2IDO1KMT2AMDM4
SCHEMBL16167663 0.90 CTSK (0.47) HDAC1HDAC2IDO1KMT2ATNF
SCHEMBL18718108 0.90 CASP3 (0.51) HDAC1HDAC2IDO1KMT2AMDM4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250263365-A1 O-SUBSTITUTED SERINE DERIVATIVE PRODUCTION METHOD CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2025-08-21 — — US disclosed
EP-3878836-B1 O-SUBSTITUTED SERINE DERIVATIVE PRODUCTION METHOD CHUGAI PHARMACEUTICAL CO LTD (JP) 2025-07-23 — — EP disclosed
US-12312297-B2 O-substituted serine derivative production method CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2025-05-27 — — US disclosed
EP-4425181-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE Bertis Inc (KR) 2024-09-04 — — EP disclosed
CN-112969683-B Process for the preparation of O-substituted serine derivatives 中外制药株式会社 2024-05-14 — — CN disclosed
US-20240011979-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTES BERTIS INC. (KR) 2024-01-11 — — US disclosed
CN-116829949-A Compositions for detecting or measuring analytes 伯蒂斯有限公司 2023-09-29 — — CN disclosed
WO-2023075435-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE 주식회사 베르티스 2023-05-04 — — WO disclosed
US-20220283131-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTES BERTIS CO., LTD. (KR) 2022-09-08 — — US disclosed
WO-2022050529-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE ㈜베르티스 2022-03-10 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250263365-A1 O-SUBSTITUTED SERINE DERIVATIVE PRODUCTION METHOD STS, SMOX, TST HDAC1 4027/4885HDAC2 4004/4885IDO1 1734/4885
US-12312297-B2 O-substituted serine derivative production method STS, SMOX, TST HDAC1 4027/4885HDAC2 4004/4885IDO1 1734/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback