Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | HTR1D | P28221 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | HTR1E | P28566 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9160128 | 1.00 | ALDH1A1 (0.37) | ALDH1A1LMNAHTTALOX5C5AR1 | |
| SCHEMBL9158117 | 0.90 | ALDH1A1 (0.48) | ALDH1A1LMNAHTTALOX5C5AR1 | |
| SCHEMBL19288030 | 0.90 | ALDH1A1 (0.38) | ALDH1A1LMNAHTTALOX5C5AR1 | |
| SCHEMBL4557934 | 0.88 | ALDH1A1 (0.46) | ALDH1A1LMNAHTTALOX5SIGMAR1 | |
| SCHEMBL9156964 | 0.83 | KMT2A (0.35) | ALDH1A1LMNAHTTALOX5GAA | |
| SCHEMBL8911526 | 0.80 | — | — | |
| SCHEMBL17629031 | 0.79 | ALDH1A1 (0.38) | ALDH1A1LMNAHTTALOX5C5AR1 | |
| SCHEMBL1509676 | 0.78 | KDM4E (0.45) | ALDH1A1C5AR1GAAOPRK1SLC6A2 | |
| SCHEMBL9757638 | 0.78 | OPRM1 (0.34) | ALDH1A1LMNAOPRK1OPRM1OPRD1 | |
| SCHEMBL1509825 | 0.77 | KDM4E (0.39) | ALDH1A1C5AR1GAAOPRK1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5198134-A | Antioxidants for lubricants | CIBA-GEIGY CORPORATION (US) | 1993-03-30 | — | — | US | disclosed |