Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.62 |
| ▸ | GLA | P06280 | 1/20 | 0.62 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.60 |
| ▸ | MYC | P01106 | 1/20 | 0.51 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.51 |
| ▸ | SORT1 | Q99523 | 9/20 | 0.46 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.46 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.46 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.46 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.46 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.46 |
| ▸ | PIM1 | P11309 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CES2 | O00748 | 1/20 | 0.45 |
| ▸ | GALR3 | O60755 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9450696 | 0.92 | KDM4E (0.62) | KDM4EGLADGAT1MYCNR4A1 | |
| SCHEMBL2344362 | 0.89 | DGAT1 (0.67) | KDM4EGLADGAT1MYCNR4A1 | |
| SCHEMBL618056 | 0.87 | KDM4E (0.65) | KDM4EGLAMYCNR4A1SORT1 | |
| SCHEMBL4441828 | 0.85 | KDM4E (0.63) | KDM4EGLAMYCNR4A1SORT1 | |
| SCHEMBL27850589 | 0.84 | SORT1 (0.52) | KDM4EGLADGAT1MYCNR4A1 | |
| SCHEMBL30016780 | 0.80 | MAPT (0.70) | KDM4EDGAT1POLBMAPTCASP1 | |
| SCHEMBL1719602 | 0.80 | MAPT (0.70) | KDM4EDGAT1POLBMAPTCASP1 | |
| SCHEMBL23092224 | 0.79 | KDM4E (0.57) | KDM4EGLAMYCNR4A1SORT1 | |
| SCHEMBL26740884 | 0.79 | KDM4E (0.57) | KDM4EGLAMYCNR4A1SORT1 | |
| SCHEMBL2853526 | 0.78 | DGAT1 (0.59) | KDM4EGLADGAT1PIM1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101528690-A | Isoindoline derivatives for the treatment of arrhythmias | ASTRAZENECA AB (SE) | 2009-09-09 | — | — | CN | disclosed |
| EP-0482668-B1 | HEAT SENSITIVE RECORDING MATERIAL | KANZAKI PAPER MANUFACTURING COMPANY LIMITED (JP) | 1993-08-04 | — | — | EP | disclosed |
| US-5187143-A | Thermographic mixture of basic leuco dye and color developer comprising a zinc salt of terephthaldehydic acid or a composite salt also containing an aromatic acid | KANZAKI PAPER MANUFACTURING CO., LTD. (JP) | 1993-02-16 | — | — | US | disclosed |
| EP-0482668-A1 | Heat sensitive recording material | KANZAKI PAPER MANUFACTURING COMPANY LIMITED (JP) | 1992-04-29 | — | — | EP | disclosed |
| US-4328339-A | Continuous preparation of isatoic anhydride | BASF AKTIENGESELLSCHAFT (DE) | 1982-05-04 | — | — | US | disclosed |
| US-3984406-A | FROM AN ALKALI METAL PHTHALAMATE AND A HYPOHALITE IN A HALOGEN CATALYST | BASF AKTIENGESELLSCHAFT (DT) | 1976-10-05 | — | — | US | disclosed |