SCHEMBL2344362

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL9450696	0.89	KDM4E (0.62)	DGAT1KDM4EGLACASP1CES2
	SCHEMBL9450697	0.89	KDM4E (0.62)	DGAT1KDM4EGLACASP1CES2
	SCHEMBL2853526	0.84	DGAT1 (0.59)	DGAT1KDM4EGLACASP1CES2
	SCHEMBL29435112	0.84	DGAT1 (0.59)	DGAT1KDM4EGLACASP1CES2
	SCHEMBL20808925	0.84	DGAT1 (0.64)	DGAT1KDM4EGLACASP1CES2
	SCHEMBL3488897	0.82	ALDH1A1 (0.62)	DGAT1KDM4EGLACASP1CES2
	SCHEMBL7370270	0.82	DGAT1 (0.53)	DGAT1KDM4EGLACASP1HPGD
	SCHEMBL1175614	0.82	HPGD (0.69)	DGAT1KDM4EGLACASP1CES2
	SCHEMBL13740129	0.82	DGAT1 (0.62)	DGAT1KDM4EGLACASP1CES2
	SCHEMBL5759947	0.82	DGAT1 (0.57)	DGAT1KDM4EGLACASP1CES2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.