Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.52 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.46 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.46 |
| ▸ | SCD | O00767 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | RBP4 | P02753 | 3/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2637084 | 0.86 | EPHX2 (0.44) | EPHX2SLC6A4SLC6A2SLC6A3GRIN1 | |
| SCHEMBL9450869 | 0.82 | EPHX2 (0.48) | EPHX2SLC6A4SLC6A2SLC6A3SCD | |
| SCHEMBL9450771 | 0.82 | OXTR (0.54) | GRIN1GRIN2BRBP4 | |
| SCHEMBL2637086 | 0.82 | RBP4 (0.48) | EPHX2SLC6A4SLC6A2SLC6A3GRIN1 | |
| SCHEMBL9450748 | 0.81 | RBP4 (0.51) | RBP4 | |
| SCHEMBL2636677 | 0.79 | EPHX2 (0.51) | EPHX2SLC6A4SLC6A2SLC6A3SCD | |
| SCHEMBL9477316 | 0.78 | SCD (0.51) | EPHX2SLC6A2SLC6A3GRIN1GRIN2B | |
| SCHEMBL10608410 | 0.77 | EPHX2 (0.46) | EPHX2SCD | |
| SCHEMBL21222267 | 0.77 | SLC6A4 (0.57) | EPHX2SLC6A4SLC6A2SLC6A3GRIN1 | |
| SCHEMBL20064210 | 0.77 | SLC6A4 (0.57) | EPHX2SLC6A4SLC6A2SLC6A3GRIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0560905-A1 | 3-[2-CHLORO-4-(TRIFLUOROMETHYL)PHENOXY]-1-AZETIDINE CARBOXAMIDES HAVING ANTICONVULSANT ACTIVITY. | ROBINS CO INC A H (US) | 1993-09-22 | — | — | EP | disclosed |
| WO-1992010474-A1 | 3-[2-CHLORO-4-(TRIFLUOROMETHYL)PHENOXY]-1-AZETIDINE CARBOXAMIDES HAVING ANTICONVULSANT ACTIVITY | A.H. ROBINS COMPANY, INCORPORATED (US) | 1992-06-25 | — | — | WO | disclosed |
| US-5095014-A | 3-(2-chloro-4-(trifluoromethyl)phenoxy)-1-azetidine carboxamides having anticonvulsant activity | A. H. ROBINS COMPANY, INCORPORATED (US) | 1992-03-10 | — | — | US | disclosed |