Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.48 |
| ▸ | SCD | O00767 | 3/20 | 0.46 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.45 |
| ▸ | RBP4 | P02753 | 3/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9450773 | 0.84 | OXTR (0.53) | SCN9ARBP4 | |
| SCHEMBL9450847 | 0.83 | RBP4 (0.50) | EPHX2SCN9ARBP4 | |
| SCHEMBL9450737 | 0.82 | EPHX2 (0.52) | EPHX2SCDRBP4SLC6A4SLC6A2 | |
| SCHEMBL9595686 | 0.81 | KAT2B (0.48) | RBP4SLC6A3 | |
| SCHEMBL9450846 | 0.80 | RBP4 (0.66) | EPHX2SCDSCN9ARBP4 | |
| SCHEMBL9450786 | 0.80 | SCN9A (0.41) | SCDSCN9ASLC6A2 | |
| SCHEMBL9596043 | 0.79 | USP30 (0.54) | EPHX2SCDRBP4 | |
| SCHEMBL2637084 | 0.78 | EPHX2 (0.44) | EPHX2SCDRBP4SLC6A4SLC6A2 | |
| SCHEMBL9354289 | 0.78 | SCN9A (0.51) | SCN9ARBP4 | |
| SCHEMBL9450778 | 0.78 | SCD (0.46) | SCDSCN9ARBP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0560905-A1 | 3-[2-CHLORO-4-(TRIFLUOROMETHYL)PHENOXY]-1-AZETIDINE CARBOXAMIDES HAVING ANTICONVULSANT ACTIVITY. | ROBINS CO INC A H (US) | 1993-09-22 | — | — | EP | disclosed |
| WO-1992010474-A1 | 3-[2-CHLORO-4-(TRIFLUOROMETHYL)PHENOXY]-1-AZETIDINE CARBOXAMIDES HAVING ANTICONVULSANT ACTIVITY | A.H. ROBINS COMPANY, INCORPORATED (US) | 1992-06-25 | — | — | WO | disclosed |
| US-5095014-A | 3-(2-chloro-4-(trifluoromethyl)phenoxy)-1-azetidine carboxamides having anticonvulsant activity | A. H. ROBINS COMPANY, INCORPORATED (US) | 1992-03-10 | — | — | US | disclosed |