Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.42 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | FNTA | P49354 | 1/20 | 0.35 |
| ▸ | FNTB | P49356 | 1/20 | 0.35 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.34 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2534881 | 0.94 | GPR84 (0.43) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL7613776 | 0.89 | AKR1B1 (0.48) | ALDH1A1THRBFNTAFNTBPGGT1B | |
| Ethylene Glycol SCHEMBL10952282 | 0.89 | HDAC3 (0.43) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL523411 | 0.89 | CAMK2A (0.52) | CAMK2ATBXAS1FNTAFNTBGPR84 | |
| SCHEMBL16091 | 0.89 | — | — | |
| SCHEMBL7607615 | 0.88 | CES2 (0.39) | CAMK2ATBXAS1ALDH1A1THRBFNTA | |
| SCHEMBL7155030 | 0.88 | GPR84 (0.50) | ALDH1A1THRBFNTAFNTBPGGT1B | |
| SCHEMBL1534015 | 0.87 | CAMK2A (0.42) | CAMK2AFFAR3TBXAS1ALDH1A1THRB | |
| SCHEMBL3862256 | 0.86 | CES1 (0.46) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| Acetone SCHEMBL8337322 | 0.86 | CAMK2A (0.46) | CAMK2ATBXAS1THRBFNTAFNTB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0537338-A1 | THERMALLY STABLE COMPOSITIONS AND LUBRICANTS AND FUNCTIONAL FLUIDS CONTAINING THE SAME. | LUBRIZOL CORP (US) | 1993-04-21 | — | — | EP | disclosed |