Acetone

Acetone

SCHEMBL8337322

C=C(CCCO)C(=O)O.CC(C)=O

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CAMK2A Q9UQM7 1/20 0.46
TBXAS1 P24557 2/20 0.40
GPR84 Q9NQS5 1/20 0.37
FFAR1 O14842 1/20 0.37
FFAR4 Q5NUL3 1/20 0.37
TET2 Q6N021 4/20 0.35
FNTA P49354 2/20 0.33
FNTB P49356 2/20 0.33
TET3 O43151 1/20 0.33
TET1 Q8NFU7 1/20 0.33
THRB P10828 1/20 0.33
PGGT1B P53609 1/20 0.33
GRIK1 P39086 1/20 0.32
GRIK2 Q13002 1/20 0.32
GRM1 Q13255 1/20 0.32
GRM2 Q14416 1/20 0.32
ALOX15 P16050 1/20 0.32
HSD17B10 Q99714 1/20 0.32
KDM4E B2RXH2 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methacrylic Acid SCHEMBL5870670 0.93 CAMK2A (0.44) CAMK2ATBXAS1GPR84FFAR1FFAR4
SCHEMBL523411 0.93 CAMK2A (0.52) CAMK2ATBXAS1GPR84FFAR1FFAR4
SCHEMBL16091 0.93
SCHEMBL3458521 0.88 CAMK2A (0.48) CAMK2ATBXAS1GPR84FFAR1FFAR4
SCHEMBL1043051 0.87 ALDH1A1 (0.40) CAMK2ATBXAS1GPR84FFAR1FFAR4
SCHEMBL9450765 0.86 CAMK2A (0.42) CAMK2ATBXAS1GPR84FFAR1FFAR4
SCHEMBL1534015 0.86 CAMK2A (0.42) CAMK2ATBXAS1GPR84FFAR1FFAR4
Methacrylic Acid SCHEMBL5684715 0.86 GPR84 (0.44) CAMK2ATBXAS1GPR84FFAR1FFAR4
Succinic Acid SCHEMBL2218294 0.86 CAMK2A (0.59) CAMK2ATBXAS1GPR84FFAR1FFAR4
SCHEMBL16665 0.85 GPR84 (0.52) CAMK2ATBXAS1GPR84FFAR1FFAR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0914661-A1 CONDUCTIVE COMPOSITE ARTICLES BASED ON EXPANDABLE AND CONTRACTIBLE PARTICULATE MATRICES ZMS, LLC (US) 1999-05-12 EP disclosed
EP-0914661-A4 1999-05-12 EP disclosed
WO-1997015932-A1 CONDUCTIVE COMPOSITE ARTICLES BASED ON EXPANDABLE AND CONTRACTIBLE PARTICULATE MATRICES ZMS, LLC (US) 1997-05-01 WO disclosed