Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.50 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.48 |
| ▸ | ABL1 | P00519 | 1/20 | 0.47 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.47 |
| ▸ | PPARD | Q03181 | 8/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9451934 | 0.87 | ALDH1A1 (0.60) | MAPTALDH1A1KDM4EGAALMNA | |
| SCHEMBL9452001 | 0.86 | PTGS2 (0.48) | MAPTALDH1A1KDM4EGAALMNA | |
| SCHEMBL11566534 | 0.82 | ALDH1A1 (0.53) | MAPTALDH1A1KDM4EGAALMNA | |
| SCHEMBL9451865 | 0.80 | ALDH1A1 (0.53) | MAPTALDH1A1KDM4EGAALMNA | |
| SCHEMBL9451959 | 0.79 | ALDH1A1 (0.62) | MAPTALDH1A1KDM4EGAALMNA | |
| SCHEMBL9451876 | 0.78 | ALDH1A1 (0.54) | MAPTALDH1A1KDM4EGAALMNA | |
| SCHEMBL9451908 | 0.77 | MAPT (0.50) | MAPTALDH1A1KDM4EGAALMNA | |
| SCHEMBL9451931 | 0.76 | PTGS2 (0.58) | MAPTALDH1A1KDM4EGAALMNA | |
| SCHEMBL9451877 | 0.75 | MAPT (0.43) | MAPTALDH1A1KDM4EGAALMNA | |
| SCHEMBL9451868 | 0.75 | PTGS2 (0.48) | MAPTALDH1A1KDM4EGAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5229386-A | Anticoagulants, hypotensive agents, antiallergens, antiinflammatory agents | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-07-20 | — | — | US | disclosed |
| US-5145860-A | Anticoagulants, vasodilators, antiinflammatory, antiallergens, enzyme inhibitors | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-09-08 | — | — | US | disclosed |