Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | PPARD | Q03181 | 10/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9451908 | 0.89 | MAPT (0.50) | PTGS2ALDH1A1MAPTKDM4ELMNA | |
| SCHEMBL9451982 | 0.86 | MAPT (0.50) | PTGS2ALDH1A1MAPTKDM4ELMNA | |
| SCHEMBL9451934 | 0.85 | ALDH1A1 (0.60) | PTGS2ALDH1A1MAPTKDM4ELMNA | |
| SCHEMBL9451878 | 0.81 | PTGS2 (0.47) | PTGS2ALDH1A1MAPTKDM4ELMNA | |
| SCHEMBL9695284 | 0.79 | TP53 (0.48) | PTGS2ALDH1A1MAPTKDM4ELMNA | |
| SCHEMBL9451865 | 0.75 | ALDH1A1 (0.53) | PTGS2ALDH1A1MAPTKDM4ELMNA | |
| SCHEMBL9451959 | 0.75 | ALDH1A1 (0.62) | PTGS2ALDH1A1MAPTKDM4ELMNA | |
| SCHEMBL9451893 | 0.74 | MAPT (0.49) | PTGS2ALDH1A1MAPTKDM4ELMNA | |
| SCHEMBL9451876 | 0.74 | ALDH1A1 (0.54) | PTGS2ALDH1A1MAPTKDM4ELMNA | |
| SCHEMBL9451877 | 0.74 | MAPT (0.43) | PTGS2ALDH1A1MAPTKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5229386-A | Anticoagulants, hypotensive agents, antiallergens, antiinflammatory agents | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-07-20 | — | — | US | disclosed |
| US-5145860-A | Anticoagulants, vasodilators, antiinflammatory, antiallergens, enzyme inhibitors | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-09-08 | — | — | US | disclosed |
| EP-0388909-A2 | Thiazole compounds, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1990-09-26 | — | — | EP | disclosed |