Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8766941 | 0.95 | THRB (0.58) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL28491972 | 0.85 | TSHR (0.42) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL28019119 | 0.85 | THRB (0.53) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL5435399 | 0.83 | THRB (0.65) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL284797 | 0.83 | TSHR (0.42) | THRBTSHRALDH1A1TP53HIF1A | |
| SCHEMBL5382514 | 0.83 | THRB (0.52) | THRBTSHRALDH1A1POLBAPEX1 | |
| Butadiene SCHEMBL1685979 | 0.81 | THRB (0.63) | THRBTSHRALDH1A1POLBAPEX1 | |
| Propene SCHEMBL672400 | 0.81 | THRB (0.63) | THRBTSHRALDH1A1POLBAPEX1 | |
| Propene SCHEMBL11112032 | 0.81 | THRB (0.63) | THRBTSHRALDH1A1POLBAPEX1 | |
| Propene SCHEMBL8851515 | 0.81 | THRB (0.63) | THRBTSHRALDH1A1POLBAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 586 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4043508-B9 | SILICONE HYDROGELS COMPRISING N-ALKYL METHACRYLAMIDES AND CONTACT LENSES MADE THEREOF | JOHNSON & JOHNSON VISION CARE (US) | 2025-10-08 | — | — | EP | claimed |
| EP-4043508-B1 | SILICONE HYDROGELS COMPRISING N-ALKYL METHACRYLAMIDES AND CONTACT LENSES MADE THEREOF | JOHNSON & JOHNSON VISION CARE (US) | 2025-04-09 | — | — | EP | claimed |
| EP-3569623-B1 | VINYL-LACTAM-BASED HYDROGEL COATINGS | CONSEJO SUPERIOR INVESTIGACION (ES) | 2023-08-09 | — | — | EP | claimed |
| US-10988591-B2 | Vinyl-lactam-based hydrogel coatings | CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (CSIC) | 2021-04-27 | — | — | US | claimed |
| EP-3569623-A1 | VINYL-LACTAM-BASED HYDROGEL COATINGS | Consejo Superior de Investigaciones Cientificas (CSIC) (ES) | 2019-11-20 | — | — | EP | claimed |
| EP-3481876-A1 | SILICONE HYDROGELS COMPRISING N-ALKYL METHACRYLAMIDES AND CONTACT LENSES MADE THEREOF | Johnson & Johnson Vision Care Inc. (US) | 2019-05-15 | — | — | EP | claimed |
| CN-109689714-A | Silicone hydrogels comprising N-alkylmethacrylamides and contact lenses made therefrom | 庄臣及庄臣视力保护公司 | 2019-04-26 | — | — | CN | claimed |
| US-20180244927-A1 | COATING COMPOSITION AND USES THEREOF | THE QUEEN'S UNIVERSITY OF BELFAST (GB) | 2018-08-30 | — | — | US | claimed |
| US-20180011223-A1 | SILICONE HYDROGELS COMPRISING N-ALKYL METHACRYLAMIDES AND CONTACT LENSES MADE THEREOF | JOHNSON & JOHNSON VISION CARE, INC. | 2018-01-11 | — | — | US | claimed |
| WO-2018009312-A1 | SILICONE HYDROGELS COMPRISING N-ALKYL METHACRYLAMIDES AND CONTACT LENSES MADE THEREOF | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2018-01-11 | — | — | WO | claimed |
| WO-1996040810-A1 | POLYMER COMPOSITIONS FOR CONTACT LENSES | BAUSCH & LOMB INCORPORATED (US) | 1996-12-19 | — | — | WO | claimed |
| EP-0611379-B1 | WETTABLE SILICONE HYDROGEL COMPOSITIONS AND METHODS FOR THEIR MANUFACTURE | BAUSCH & LOMB (US) | 1996-05-29 | — | — | EP | claimed |
| US-5512205-A | BIOMEDICAL ARTICLES, CONTACT LENSES | BAUSCH & LOMB INCORPORATED (US) | 1996-04-30 | — | — | US | claimed |
| US-5449729-A | Vinyl monomer and crosslinking agent and acrylates with styrene | BAUSCH & LOMB INCORPORATED (US) | 1995-09-12 | — | — | US | claimed |
| WO-1995017689-A1 | METHOD FOR INCREASING HYDROPHILICITY OF CONTACT LENSES | BAUSCH & LOMB INCORPORATED (US) | 1995-06-29 | — | — | WO | claimed |
| EP-0611379-A1 | WETTABLE SILICONE HYDROGEL COMPOSITIONS AND METHODS FOR THEIR MANUFACTURE. | BAUSCH & LOMB (US) | 1994-08-24 | — | — | EP | claimed |
| EP-0611367-A1 | NOVEL UV CURABLE CROSSLINKING AGENTS USEFUL IN COPOLYMERIZATION. | BAUSCH & LOMB (US) | 1994-08-24 | — | — | EP | claimed |
| US-5310779-A | Compatible crosslinkers having vinyl-, acrylic-and/or styrenyl-groups to crosslink incompatible unsaturated addition monomers; contact lens; molding materials | BAUSCH & LOMB INCORPORATED (US) | 1994-05-10 | — | — | US | claimed |
| WO-1993009154-A1 | WETTABLE SILICONE HYDROGEL COMPOSITIONS AND METHODS FOR THEIR MANUFACTURE | BAUSCH & LOMB INCORPORATED (US) | 1993-05-13 | — | — | WO | claimed |
| WO-1993009084-A1 | NOVEL UV CURABLE CROSSLINKING AGENTS USEFUL IN COPOLYMERIZATION | BAUSCH & LOMB INCORPORATED (US) | 1993-05-13 | — | — | WO | claimed |