SCHEMBL9452579

SCHEMBL9452579

C=CC(=O)NC(=O)C(=O)OCC

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EGLN1 Q9GZT9 1/20 0.46
ZDHHC20 Q5W0Z9 1/20 0.40
ZDHHC2 Q9UIJ5 1/20 0.40
NPSR1 Q6W5P4 1/20 0.39
GLO1 Q04760 1/20 0.39
ALDH1A1 P00352 6/20 0.39
SMN1; SMN2 Q16637 3/20 0.39
CYP2D6 P10635 1/20 0.39
GAA P10253 5/20 0.39
MAPT P10636 1/20 0.39
HTT P42858 1/20 0.39
TSHR P16473 2/20 0.38
MGAM O43451 1/20 0.38
SI P14410 1/20 0.38
MGAM2 Q2M2H8 1/20 0.38
GPR35 Q9HC97 2/20 0.38
TDP1 Q9NUW8 3/20 0.37
MAPK1 P28482 1/20 0.37
NPC1 O15118 1/20 0.37
RAB9A P51151 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9683114 0.82 ALDH1A1 (0.41) EGLN1ZDHHC20ZDHHC2NPSR1GLO1
SCHEMBL10896390 0.82 GAA (0.45) EGLN1ZDHHC20ZDHHC2NPSR1GLO1
SCHEMBL93928 0.79 GAA (0.41) ZDHHC20ZDHHC2ALDH1A1GAATSHR
SCHEMBL28470284 0.79 TSHR (0.39) EGLN1ZDHHC20ZDHHC2ALDH1A1TSHR
SCHEMBL10934328 0.78 ALDH1A1 (0.38) EGLN1ZDHHC20ZDHHC2NPSR1GLO1
SCHEMBL8755750 0.78 GAA (0.39) ZDHHC20ZDHHC2ALDH1A1GAATSHR
SCHEMBL27963209 0.78 GAA (0.39) ZDHHC20ZDHHC2ALDH1A1GAATSHR
SCHEMBL21728959 0.77 ZDHHC20 (0.64) EGLN1ZDHHC20ZDHHC2ALDH1A1GAA
SCHEMBL3169315 0.74 NPSR1 (0.38) EGLN1ZDHHC20ZDHHC2NPSR1GLO1
SCHEMBL9452562 0.73 EGLN1 (0.47) EGLN1GLO1ALDH1A1SMN1; SMN2GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5208308-A N-Oxalyl-Substituted NIPPON PAINT CO., LTD. (JP) 1993-05-04 US claimed
US-5274062-A An N-(substituted oxalyl)-halopropionamide NIPPON PAINT CO., LTD. (JP) 1993-12-28 US disclosed
US-5208308-A N-Oxalyl-Substituted NIPPON PAINT CO., LTD. (JP) 1993-05-04 US disclosed
US-4970281-A COATINGS, ADHESIVES, MOLDING NIPPON PAINT CO., LTD. (JP) 1990-11-13 US disclosed
US-4956491-A MONOMERS FOR RESINS USED IN COATINGS, ADHESIVES OR MOLDING MATERIALS NIPPON PAINT CO., LTD. (JP) 1990-09-11 US disclosed
US-4914225-A MOLDING MATERIALS, COATINGS, ADHESIVES NIPPON PAINT CO., LTD. (JP) 1990-04-03 US disclosed
EP-0243207-A2 Alpha-alkylacrylamide derivatives and their polymers Nippon Paint Co., Ltd. (JP) 1987-10-28 EP disclosed
EP-0243208-A2 Acrylamide derivatives and their polymers Nippon Paint Co., Ltd. (JP) 1987-10-28 EP disclosed