⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL946960 | 0.89 | — | — | |
| SCHEMBL947266 | 0.88 | NOS3 (0.32) | — | |
| SCHEMBL946810 | 0.88 | SIGMAR1 (0.32) | — | |
| SCHEMBL3505792 | 0.83 | — | — | |
| SCHEMBL948954 | 0.82 | — | — | |
| SCHEMBL2913288 | 0.81 | NOS3 (0.32) | — | |
| SCHEMBL789308 | 0.78 | — | — | |
| SCHEMBL6559713 | 0.78 | — | — | |
| SCHEMBL477202 | 0.78 | — | — | |
| SCHEMBL947605 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1135379-B1 | ANTITUMOR DIBENZOFLUORENE DERIVATIVES | REGENTS BOARD OF (US) | 2004-10-06 | — | — | EP | claimed |
| US-20020103191-A1 | Antitumor dibenzofluorene derivatives | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM | 2002-08-01 | — | — | US | claimed |
| EP-1135379-A1 | ANTITUMOR DIBENZOFLUORENE DERIVATIVES | Board of Regents, The University of Texas System (US) | 2001-09-26 | — | — | EP | claimed |
| US-6184224-B1 | DRUG RESISTANCE AND SIDE EFFECT REDUCTION | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM | 2001-02-06 | — | — | US | claimed |
| WO-2000032583-A9 | ANTITUMOR DIBENZOFLUORENE DERIVATIVES | UNIV TEXAS (US) | 2000-11-30 | — | — | WO | claimed |
| WO-2000032583-A1 | ANTITUMOR DIBENZOFLUORENE DERIVATIVES | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2000-06-08 | — | — | WO | claimed |
| EP-0675169-B1 | Cationic thiadiazole dyes | BAYER AG (DE) | 1998-09-16 | — | — | EP | claimed |
| EP-0816351-A1 | Functional N-vinylformamides, process for their preparation and their use in free radical polymerisation reactions | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1998-01-07 | — | — | EP | claimed |
| US-5580964-A | USED FOR DYEING AND PRINTING PAPER IN LIGHTFAST SHADES, AS DICHROIC DYES FOR POLARIZING FILMS | BAYER AKTIENGESELLSCHAFT (DE) | 1996-12-03 | — | — | US | claimed |
| EP-0675169-A2 | Cationic thiadiazole dyes | BAYER AG (DE) | 1995-10-04 | — | — | EP | claimed |
| CN-109563043-B | Substituted pyridines as inhibitors of DNMT1 | 葛兰素史密斯克莱知识产权发展有限公司 | 2022-05-31 | — | — | CN | disclosed |
| US-7989446-B2 | 4-amino 5-cyanopyrimidine derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2011-08-02 | — | — | US | disclosed |
| US-20110009620-A1 | 4-Amino-5-cyanopyrimidine derivatives | OTSUKA PHARMACEUTICAL CO., LTD. | 2011-01-13 | — | — | US | disclosed |
| US-7834002-B2 | 4-amino-5-cyanopyrimidine derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2010-11-16 | — | — | US | disclosed |
| EP-1591443-B1 | PYRAZOLE DERIVATIVE | DAIICHI SANKYO CO LTD (JP) | 2010-08-25 | — | — | EP | disclosed |
| EP-0675169-B1 | Cationic thiadiazole dyes | BAYER AG (DE) | 1998-09-16 | — | — | EP | disclosed |
| US-5728878-A | USEFUL AS MONOMERS | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1998-03-17 | — | — | US | disclosed |
| EP-0816351-A1 | Functional N-vinylformamides, process for their preparation and their use in free radical polymerisation reactions | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1998-01-07 | — | — | EP | disclosed |
| US-5580964-A | USED FOR DYEING AND PRINTING PAPER IN LIGHTFAST SHADES, AS DICHROIC DYES FOR POLARIZING FILMS | BAYER AKTIENGESELLSCHAFT (DE) | 1996-12-03 | — | — | US | disclosed |
| EP-0675169-A2 | Cationic thiadiazole dyes | BAYER AG (DE) | 1995-10-04 | — | — | EP | disclosed |