Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.36 |
| ▸ | PTPRC | P08575 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | FGR | P09769 | 1/20 | 0.35 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.35 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
| ▸ | HIPK2 | Q9H2X6 | 1/20 | 0.35 |
| ▸ | CSNK1G1 | Q9HCP0 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6951345 | 0.81 | NOTUM (0.40) | ALDH1A1NPC1KDM4EGAAMAPT | |
| SCHEMBL27875386 | 0.78 | ALDH1A1 (0.38) | ALDH1A1L3MBTL1NPC1KDM4EHSD17B10 | |
| SCHEMBL5978346 | 0.78 | HSD11B1 (0.43) | ALDH1A1NPC1KDM4EPTPRCMAOB | |
| SCHEMBL27891853 | 0.78 | MEN1 (0.43) | NPC1GAAMAPTADORA2APTPRC | |
| SCHEMBL11046375 | 0.78 | C1R (0.37) | ALDH1A1NPC1MAPTMEN1KMT2A | |
| SCHEMBL11578516 | 0.76 | CYP2D6 (0.38) | ALDH1A1L3MBTL1NPC1DPP4MAPT | |
| SCHEMBL27667708 | 0.75 | ALDH1A1 (0.43) | ALDH1A1KDM4EMAPTADORA2APTPRC | |
| SCHEMBL182947 | 0.72 | PDE4B (0.42) | ALDH1A1L3MBTL1GAAMAPTKMT2A | |
| SCHEMBL9455156 | 0.69 | ALDH1A1 (0.39) | ALDH1A1NPC1KDM4EHSD17B10GAA | |
| SCHEMBL9435853 | 0.68 | MAP4K4 (0.42) | ADORA2AMAOBMAOAMEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1235992-A | Water-soluble fiber-reactive dyes, processes for their preparation and their use | HOECHST AG (DE) | 1999-11-24 | — | — | CN | disclosed |
| CN-1108277-A | Water-soluble fibre-reactive dyes, their preparation and their use | HOECHST AG (DE) | 1995-09-13 | — | — | CN | disclosed |
| US-5274083-A | A 2-halopyrimidinylaminoalkylamino-4-chloro-6-sulfonyl-substituted chromophore group-s-triazine | BAYER AKTIENGESELLSCHAFT (DE) | 1993-12-28 | — | — | US | disclosed |