SCHEMBL11046375

SCHEMBL11046375

CC1=C(c2ccccc2I)C(=O)N=N1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
C1R P00736 8/20 0.37
F2 P00734 1/20 0.35
PLG P00747 1/20 0.35
KLK1 P06870 1/20 0.35
PRSS1 P07477 1/20 0.35
C1S P09871 1/20 0.35
CTSG P08311 1/20 0.32
KLK7 P49862 1/20 0.32
KLK14 Q9P0G3 1/20 0.32
KLK5 Q9Y337 1/20 0.32
KCNN4 O15554 1/20 0.30
NPC1 O15118 1/20 0.30
ALDH1A1 P00352 1/20 0.30
CYP1A2 P05177 1/20 0.30
CYP3A4 P08684 1/20 0.30
MAPT P10636 1/20 0.30
CYP2C9 P11712 1/20 0.30
CASP1 P29466 1/20 0.30
CYP2C19 P33261 1/20 0.30
RAB9A P51151 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6951345 0.81 NOTUM (0.40) NPC1ALDH1A1MAPTRAB9AMEN1
SCHEMBL27891853 0.78 MEN1 (0.43) C1RF2NPC1MAPTRAB9A
SCHEMBL9455152 0.78 ALDH1A1 (0.43) NPC1ALDH1A1CYP3A4MAPTRAB9A
SCHEMBL27875386 0.78 ALDH1A1 (0.38) C1RNPC1ALDH1A1MAPTRAB9A
SCHEMBL5978346 0.78 HSD11B1 (0.43) NPC1ALDH1A1RAB9AKMT2A
SCHEMBL11578516 0.76 CYP2D6 (0.38) KCNN4NPC1ALDH1A1MAPTRAB9A
SCHEMBL27667708 0.75 ALDH1A1 (0.43) C1RALDH1A1MAPTMEN1KMT2A
SCHEMBL182947 0.72 PDE4B (0.42) ALDH1A1MAPTNPSR1CDC25BKMT2A
SCHEMBL10936826 0.66
SCHEMBL28078491 0.66 PDE4B (0.36) ALDH1A1MAPTNPSR1MEN1CDC25B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0024872-A1 A method of treating exposed and developed radiation sensitive plates in lithographic printing plate production, compositions for use in the method, and the use of diazo eliminating compounds in improving the ink receptivity of lithographic printing images Vickers Limited (GB) 1981-03-11 EP claimed
US-10182978-B2 Dyeing process using a mixture comprising a thickening polymer, obtained from an aerosol device, and device therefor L'OREAL (FR) 2019-01-22 US disclosed
US-20180078485-A1 DYEING PROCESS USING A MIXTURE COMPRISING A THICKENING POLYMER, OBTAINED FROM AN AEROSOL DEVICE, AND DEVICE THEREFOR L'OREAL (FR) 2018-03-22 US disclosed
US-20150351517-A1 HAIR COLOURING KIT CONOPCO, INC.,D/B/A UNILEVER (US) 2015-12-10 US disclosed
EP-0129527-A2 Vulcanisable rubber composition and compounds useful as stabilising agents for rubber vulcanisates MONSANTO EUROPE S.A./N.V. (BE) 1984-12-27 EP disclosed
EP-0092343-A1 New chromium complex dyestuffs, their preparation and use I.C.I. FRANCOLOR S.A. (FR) 1983-10-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10182978-B2 Dyeing process using a mixture comprising a thickening polymer, obtained from an aerosol device, and device therefor KRT18, NOTUM, HK1 C1R 2822/4885F2 4212/4885PLG 954/4885
US-20180078485-A1 DYEING PROCESS USING A MIXTURE COMPRISING A THICKENING POLYMER, OBTAINED FROM AN AEROSOL DEVICE, AND DEVICE THEREFOR KRT18, NOTUM, HKDC1 C1R 2910/4885F2 4260/4885PLG 1104/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.