Known targets — ChEMBL curated mechanism
GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BHMGCRMMP1MMP13MMP7MMP8PTGS1PTGS2ileSpolrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR known ✓ | P04035 | 4/20 | 0.48 |
| ▸ | GABBR2 known ✓ | O75899 | 1/20 | 0.47 |
| ▸ | GABBR1 known ✓ | Q9UBS5 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | GAA | P10253 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | TSHR | P16473 | 3/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | BLM | P54132 | 2/20 | 0.49 |
| ▸ | ATM | Q13315 | 2/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1567923 | 1.00 | MEN1 (0.58) | MEN1KMT2AGAAALDH1A1TSHR | |
| SCHEMBL30216005 | 0.96 | MEN1 (0.58) | MEN1KMT2AGAAALDH1A1TSHR | |
| SCHEMBL11438934 | 0.96 | MEN1 (0.58) | MEN1KMT2AGAAALDH1A1TSHR | |
| Zinc Ion SCHEMBL9419681 | 0.96 | MEN1 (0.58) | MEN1KMT2AGAAALDH1A1TSHR | |
| SCHEMBL31688385 | 0.96 | MEN1 (0.58) | MEN1KMT2AGAAALDH1A1TSHR | |
| SCHEMBL914945 | 0.96 | MEN1 (0.58) | MEN1KMT2AGAAALDH1A1TSHR | |
| Alcohol SCHEMBL28615118 | 0.92 | KMT2A (0.54) | MEN1KMT2AGAAALDH1A1TSHR | |
| SCHEMBL2719829 | 0.85 | KMT2A (0.54) | MEN1KMT2AGAAALDH1A1TSHR | |
| SCHEMBL5433354 | 0.83 | MEN1 (0.52) | MEN1KMT2AGAAALDH1A1TSHR | |
| SCHEMBL1419607 | 0.82 | HMGCR (0.52) | MEN1KMT2AGAAALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117229597-A | Nucleating agent composition for polyoxymethylene, polyoxymethylene composition and preparation method | 开滦（集团）有限责任公司 | 2023-12-15 | — | — | CN | claimed |
| CN-110352223-B | Coating composition with covalently bound UV absorber | 巴斯夫欧洲公司 | 2022-08-02 | — | — | CN | claimed |
| CN-114437264-A | Low-VOC low-odor polypropylene resin and preparation method and application thereof | 中国石油化工股份有限公司 | 2022-05-06 | — | — | CN | claimed |
| US-20250059410-A1 | PRESSURE SENSITIVE ADHESIVE CONTAINING LIQUID RESIN COMPRISING AN OLIGOESTER COMPOSITION | HENKEL AG & CO. KGAA (DE) | 2025-02-20 | — | — | US | disclosed |
| CN-119144243-A | Surface protective film | 日东电工株式会社 | 2024-12-17 | — | — | CN | disclosed |
| CN-119013346-A | Thermoplastic elastomer composition for multilayer molding, multilayer molded body, and method for producing multilayer molded body | 旭化成株式会社 | 2024-11-22 | — | — | CN | disclosed |
| CN-118946644-A | Pressure-sensitive adhesive sheet for optical use | 日东电工株式会社 | 2024-11-12 | — | — | CN | disclosed |
| CN-118906612-A | White regenerated PETG heat-shrinkable film and preparation method thereof | 河南银金达新材料股份有限公司 | 2024-11-08 | — | — | CN | disclosed |
| CN-118891972-A | Optical laminate for OLED display device | 日东电工株式会社 | 2024-11-01 | — | — | CN | disclosed |
| CN-118871542-A | Pressure-sensitive adhesive sheet for optical use | 日东电工株式会社 | 2024-10-29 | — | — | CN | disclosed |
| CN-118871293-A | Multilayer structure | 三菱化学株式会社 | 2024-10-29 | — | — | CN | disclosed |
| CN-115461381-A | Acid group-containing (meth) acrylate resin, curable resin composition, insulating material, resin material for solder resist, and resist member | DIC株式会社 | 2022-12-09 | — | — | CN | disclosed |
| CN-115335463-A | Resin composition, method for producing resin composition, molded body, multilayer structure, and package | 三菱化学株式会社 | 2022-11-11 | — | — | CN | disclosed |
| CN-115038753-A | Composition, curable composition, cured product and storage method | 株式会社钟化 | 2022-09-09 | — | — | CN | disclosed |
| CN-111205446-B | High-temperature-resistant organic amine modified polyester resin and preparation method and application thereof | 衡阳山泰化工有限公司 | 2022-08-19 | — | — | CN | disclosed |
| CN-114921047-A | Elastic rubber composition and preparation method thereof | 李焱明 | 2022-08-19 | — | — | CN | disclosed |
| CN-110352223-B | Coating composition with covalently bound UV absorber | 巴斯夫欧洲公司 | 2022-08-02 | — | — | CN | disclosed |
| CN-108473745-B | Ethylene-vinyl alcohol copolymer composition pellet and method for producing ethylene-vinyl alcohol copolymer composition pellet | 三菱化学株式会社 | 2022-07-08 | — | — | CN | disclosed |
| CN-114437264-A | Low-VOC low-odor polypropylene resin and preparation method and application thereof | 中国石油化工股份有限公司 | 2022-05-06 | — | — | CN | disclosed |
| US-5238767-A | Modified polypropylene or polyolefin; high offset temperature | SANYO CHEMICAL INDUSTRIES, LTD. (JP) | 1993-08-24 | — | — | US | disclosed |