SCHEMBL9456751

SCHEMBL9456751

C=C(C)C(=O)OCCC(O)C(CCOC(=O)C(=C)C)(CCOC(=O)C(=C)C)n1c(=O)[nH]c(=O)[nH]c1=O

nearest known ligand 0.35

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.35
THRB P10828 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9504845 0.81 TSHR (0.34) TSHRTHRB
SCHEMBL149918 0.77 THRB (0.36) TSHRTHRB
SCHEMBL8083935 0.75 THRB (0.35) TSHRTHRB
SCHEMBL6903420 0.75 THRB (0.35) TSHRTHRB
SCHEMBL21625766 0.74 TSHR (0.38) TSHRTHRB
SCHEMBL16143278 0.74 TSHR (0.38) TSHRTHRB
SCHEMBL149919 0.73 THRB (0.37) TSHRTHRB
SCHEMBL7638251 0.71 TSHR (0.37) TSHRTHRB
SCHEMBL831001 0.70 THRB (0.42) TSHRTHRB
SCHEMBL7932639 0.70 TSHR (0.33) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0348063-B1 THERMOPLASTIC ELASTOMER AND PHOTOSENSITIVE RESIN COMPOSITION BASED THEREON, AND PRINTING PLATE PRECURSOR COMPRISING THE COMPOSITION Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1993-05-26 EP disclosed
US-5177171-A SULFONIC ACID GROUP-CONTAINING POLYURETHANE AND A PHOTOSENSITIVE RESIN COMPOSITION CONTAINING THE SAME ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1993-01-05 US disclosed
US-5053316-A THERMOPLASTIC ELASTOMER AND PHOTOSENSITIVE RESIN COMPOSITION BASED THEREON, AND PRINTING PLATE PRECURSOR COMPRISING THE COMPOSITION ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1991-10-01 US disclosed
EP-0348063-A1 Thermoplastic elastomer and photosensitive resin composition based thereon, and printing plate precursor comprising the composition Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1989-12-27 EP disclosed