SCHEMBL149919

SCHEMBL149919

C=C(C)C(=O)OCCC(O)(CCOC(=O)C(=C)C)Cn1c(=O)[nH]c(=O)[nH]c1=O

nearest known ligand 0.37

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.37
TSHR P16473 3/20 0.36
ALDH1A1 P00352 1/20 0.33
POLB P06746 1/20 0.32
APEX1 P27695 1/20 0.32
HTT P42858 1/20 0.32
TDP1 Q9NUW8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL153712 0.82 TSHR (0.39) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL831001 0.81 THRB (0.42) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL153868 0.81 TSHR (0.41) THRBTSHRPOLBAPEX1HTT
SCHEMBL152169 0.79 TSHR (0.39) THRBTSHRALDH1A1
SCHEMBL328926 0.78 TSHR (0.32) TSHR
SCHEMBL9796945 0.78 TSHR (0.46) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL8083935 0.77 THRB (0.35) THRBTSHRPOLBAPEX1HTT
SCHEMBL28004954 0.77 TSHR (0.43) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL28004958 0.77 TSHR (0.49) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL149918 0.77 THRB (0.36) THRBTSHRPOLBAPEX1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 172 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024075471-A1 ACRYLIC COMPOUND CONTAINING FLUOROPOLYETHER GROUP, ACTINIC-RAY-CURABLE COMPOSITION, CURED COATING FILM FORMED FROM SAID CURABLE COMPOSITION, AND ARTICLE 信越化学工業株式会社 2024-04-11 WO disclosed
EP-4342922-A1 FLUOROACRYLIC COMPOSITION, FLUOROCHEMICAL ACTINIC-RAY-CURABLE COMPOSITION, AND ARTICLE SHIN-ETSU CHEMICAL CO., LTD. (JP) 2024-03-27 EP disclosed
WO-2024057723-A1 PHOTOCURABLE COATING COMPOSITION AND COATED ARTICLE 信越化学工業株式会社 2024-03-21 WO disclosed
EP-3603954-B1 POLYMER SUBSTRATE WITH HARD COAT LAYER TEIJIN LTD (JP) 2024-03-20 EP disclosed
CN-112005140-B Partially optically active material, and partially optically active film, intermediate film laminate, functional glass and head-up display using the same 日本化药株式会社 2024-02-23 CN disclosed
US-11897989-B2 Fluorine-containing curable composition and article SHIN-ETSU CHEMICAL CO., LTD. (JP) 2024-02-13 US disclosed
EP-3441802-B1 OPTICAL FILM FOR EYEWEAR, AND OPTICAL LAMINATE AND EYEWEAR USING THE OPTICAL FILM NIPPON KAYAKU KK (JP) 2024-01-17 EP disclosed
US-11866564-B2 Polymer substrate with hard coat layer TEIJIN LIMITED (JP) 2024-01-09 US disclosed
US-20230357479-A1 PIGMENT DISPERSANT COMPOSITION, PRODUCTION METHOD THEREFOR, PIGMENT DISPERSION, AND ACTINIC-RAY-CURABLE INK-JET INK DAINICHISEIKA COLOR & CHEMICALS MFG. CO., LTD. (JP) 2023-11-09 US disclosed
CN-116964498-A Optical laminate 日本化药株式会社 2023-10-27 CN disclosed
EP-1559745-A1 LIQUID CRYSTAL COMPOUND COMPOSITION AND RETARDATION FILM USING SAME Nippon Kayaku Kabushiki Kaisha (JP) 2005-08-03 EP disclosed
US-20050118380-A1 optical recording media comprising support substrates having data recording surfaces and light transmission layer having excellent transparency, wear resistance and recording film protective ability, used for high density recording using blue lasers MITSUBISHI RAYON CO., LTD. (JP) 2005-06-02 US disclosed
EP-1484756-A1 OPTICAL INFORMATION MEDIUM TDK Corporation (JP) 2004-12-08 EP disclosed
EP-0742244-B1 Durable polysulfide composition for optical material MITSUI CHEMICALS INC (JP) 2004-08-11 EP disclosed
EP-0751161-B1 Sulfur-containing urethane-based resin composition, optical element and lens comprising this resin MITSUI CHEMICALS INC (JP) 2003-01-02 EP disclosed
US-5955206-A POLYTHIOETHERS AND ACRYLATE OR VINYL GROUPS FOR CURING TO FORM OPTICAL LENSES MITSUI CHEMICALS, INC. (JP) 1999-09-21 US disclosed
US-5736609-A A POLYTHIO COMPOUND CONTAINING AT LEAST TWO MERCAPTO GROUPS, A POLYISO(THIO)CYANATE COMPOUND, AND A COMPOUND HAVING TWO OR MORE UNSATURATED REACTIVE GROUPS MITSUI TOATSU CHEMICALS, INC. (JP) 1998-04-07 US disclosed
EP-0751161-A2 Sulfur-containing urethane-based resin composition, optical element and lens comprising this resin MITSUI TOATSU CHEMICALS, Inc. (JP) 1997-01-02 EP disclosed
EP-0742244-A2 Durable polysulfide composition for optical material MITSUI TOATSU CHEMICALS, INC. (JP) 1996-11-13 EP disclosed
EP-0243501-A1 CURABLE COMPOSITION AND METHOD FOR MOLDING IT SHOWA DENKO KABUSHIKI KAISHA (JP) 1987-11-04 EP disclosed