Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9825750 | 0.86 | TLR2 (0.33) | — | |
| SCHEMBL9457333 | 0.85 | FFAR4 (0.33) | MEN1KMT2A | |
| SCHEMBL9457037 | 0.83 | KMT2A (0.35) | MEN1KMT2A | |
| SCHEMBL9457043 | 0.83 | KMT2A (0.35) | MEN1KMT2A | |
| SCHEMBL9457001 | 0.83 | KMT2A (0.35) | MEN1KMT2A | |
| SCHEMBL9457048 | 0.83 | KMT2A (0.35) | MEN1KMT2A | |
| SCHEMBL9865919 | 0.83 | KMT2A (0.35) | MEN1KMT2A | |
| SCHEMBL8780209 | 0.81 | KMT2A (0.39) | MEN1KMT2A | |
| SCHEMBL12446846 | 0.81 | KMT2A (0.39) | MEN1KMT2A | |
| SCHEMBL2030944 | 0.81 | ALOX5 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5246960-A | Used to treat obesity, hyperlipaemia, atherosclerosis and arteriosclerosis | HOFFMANN-LA ROCHE INC. (US) | 1993-09-21 | — | — | US | disclosed |
| US-5175186-A | Inhibits pancreas lepase and useful agent in treatment of obesity, hyperlipemia, atherosclerosis and arteriosclerosis | HOFFMANN-LA ROCHE INC. (US) | 1992-12-29 | — | — | US | disclosed |
| US-4983746-A | Oxetanones and process for their production | HOFFMANN-LA ROCHE INC. (US) | 1991-01-08 | — | — | US | disclosed |
| US-4931463-A | PANCREAS LIPASE INHIBITORS | HOFFMANN-LA ROCHE INC. (US) | 1990-06-05 | — | — | US | disclosed |