Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | PTGER2 | P43116 | 4/20 | 0.32 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.32 |
| ▸ | PTGFR | P43088 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | PTGER4 | P35408 | 5/20 | 0.31 |
| ▸ | PTGER3 | P43115 | 3/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.31 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.31 |
| ▸ | RARB | P10826 | 1/20 | 0.31 |
| ▸ | RARG | P13631 | 1/20 | 0.31 |
| ▸ | DRD1 | P21728 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9457010 | 0.85 | MEN1 (0.32) | MEN1KMT2A | |
| SCHEMBL3707695 | 0.82 | FFAR4 (0.46) | FFAR4FFAR1ALDH1A1TSHRMEN1 | |
| SCHEMBL10539802 | 0.79 | PTGFR (0.46) | PTGER2TBXA2RPTGFRALDH1A1PTGER4 | |
| SCHEMBL9825750 | 0.77 | TLR2 (0.33) | — | |
| SCHEMBL2030947 | 0.76 | ALOX5 (0.32) | — | |
| SCHEMBL2030944 | 0.76 | ALOX5 (0.32) | — | |
| SCHEMBL2030946 | 0.76 | ALOX5 (0.32) | — | |
| SCHEMBL10537899 | 0.76 | PTGFR (0.42) | PTGER2TBXA2RPTGFRALDH1A1PTGER3 | |
| SCHEMBL10538424 | 0.76 | PTGFR (0.42) | PTGER2TBXA2RPTGFRALDH1A1PTGER3 | |
| SCHEMBL10603626 | 0.75 | SPHK1 (0.32) | ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5246960-A | Used to treat obesity, hyperlipaemia, atherosclerosis and arteriosclerosis | HOFFMANN-LA ROCHE INC. (US) | 1993-09-21 | — | — | US | disclosed |