Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 2/20 | 0.35 |
| ▸ | DGKA | P23743 | 1/20 | 0.35 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9457408 | 1.00 | FFAR1 (0.41) | FFAR1FFAR4GPR84FAAHPPARG | |
| SCHEMBL9457411 | 1.00 | FFAR1 (0.41) | FFAR1FFAR4GPR84FAAHPPARG | |
| SCHEMBL9457356 | 1.00 | FFAR1 (0.41) | FFAR1FFAR4GPR84FAAHPPARG | |
| SCHEMBL9457278 | 0.97 | NFKB1 (0.40) | FFAR1FFAR4PPARG | |
| SCHEMBL9457270 | 0.97 | NFKB1 (0.40) | FFAR1FFAR4PPARG | |
| Hexane SCHEMBL9734238 | 0.94 | GPR84 (0.46) | FFAR1FFAR4GPR84 | |
| SCHEMBL9457366 | 0.91 | FFAR1 (0.39) | FFAR1FFAR4FAAHPPARG | |
| SCHEMBL9457402 | 0.91 | FFAR1 (0.39) | FFAR1FFAR4FAAHPPARG | |
| SCHEMBL9457394 | 0.91 | FFAR1 (0.39) | FFAR1FFAR4FAAHPPARG | |
| SCHEMBL9457388 | 0.91 | FFAR1 (0.39) | FFAR1FFAR4FAAHPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5246960-A | Used to treat obesity, hyperlipaemia, atherosclerosis and arteriosclerosis | HOFFMANN-LA ROCHE INC. (US) | 1993-09-21 | — | — | US | disclosed |
| US-5175186-A | Inhibits pancreas lepase and useful agent in treatment of obesity, hyperlipemia, atherosclerosis and arteriosclerosis | HOFFMANN-LA ROCHE INC. (US) | 1992-12-29 | — | — | US | disclosed |
| US-4931463-A | PANCREAS LIPASE INHIBITORS | HOFFMANN-LA ROCHE INC. (US) | 1990-06-05 | — | — | US | disclosed |