Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 8/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | FYN | P06241 | 1/20 | 0.34 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NPY1R | P25929 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3138349 | 0.81 | TP53 (0.53) | TP53CYP3A4MAPK1LMNACYP1A2 | |
| SCHEMBL1607526 | 0.80 | MAOB (0.48) | MAOBFFAR1TP53CYP3A4MAPK1 | |
| SCHEMBL29411044 | 0.79 | ACHE (0.50) | MAOBCYP3A4 | |
| SCHEMBL24031 | 0.79 | ACHE (0.50) | MAOBCYP3A4 | |
| SCHEMBL3458024 | 0.79 | KMT2A (0.50) | TP53CYP3A4LMNATSHR | |
| SCHEMBL4260979 | 0.77 | NQO1 (0.36) | FYNTSHR | |
| SCHEMBL943678 | 0.76 | MAOB (0.56) | MAOBLMNA | |
| SCHEMBL30788655 | 0.76 | MAOB (0.56) | MAOBLMNA | |
| SCHEMBL2186305 | 0.76 | MAOB (0.42) | MAOBFFAR1TP53CYP3A4MAPK1 | |
| SCHEMBL2047854 | 0.75 | MAOB (0.58) | MAOBCYP3A4MAPK1LMNAAPP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3402784-B1 | 3-((HETERO-)ARYL)-ALKYL-8-AMINO-2-OXO-1,3-DIAZA-SPIRO-[4.5]-DECANE DERIVATIVES | GRUENENTHAL GMBH (DE) | 2020-03-11 | — | — | EP | disclosed |
| US-5202326-A | Inhibitor of enzyme 5-lipoxygenase; antiinflammatory and antiallergic agents | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-04-13 | — | — | US | disclosed |
| EP-0385680-A2 | Heterocyclic ethers as 5-lipoxygenase inhibitors | ZENECA LIMITED (GB) | 1990-09-05 | — | — | EP | disclosed |