Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR3 | P46089 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.44 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | CETP | P11597 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.40 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10972329 | 0.86 | MAPT (0.59) | GPR3MAPTALDH1A1GRIN1GRIN2A | |
| SCHEMBL3923640 | 0.81 | MAPT (0.50) | GPR3MAPTALDH1A1GRIN1GRIN2A | |
| SCHEMBL28221173 | 0.78 | MAPT (0.47) | GPR3MAPTALDH1A1GRIN1GRIN2A | |
| SCHEMBL30167649 | 0.78 | L3MBTL1 (0.55) | MAPTALDH1A1HTTKDM4EKMT2A | |
| SCHEMBL5843821 | 0.78 | CETP (0.47) | GPR3MAPTALDH1A1GRIN1GRIN2A | |
| SCHEMBL21246500 | 0.78 | APP (0.42) | ALDH1A1SMN1; SMN2APP | |
| SCHEMBL24305918 | 0.77 | MAPK1 (0.55) | GPR3MAPTALDH1A1GRIN1GRIN2A | |
| SCHEMBL4348572 | 0.77 | ACHE (0.50) | GPR3MAPTALDH1A1GRIN1GRIN2A | |
| SCHEMBL1471132 | 0.77 | MAOB (0.55) | GPR3MAPTALDH1A1GRIN1GRIN2A | |
| SCHEMBL10573493 | 0.77 | MAPT (0.46) | GPR3MAPTALDH1A1GRIN1GRIN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5208259-A | Lipoxygenase enzyme inhibitors | IMPERIAL CHEMICAL INDUSTRIES (GB) | 1993-05-04 | — | — | US | disclosed |
| EP-0409413-A2 | Diaryl ether heterocycles | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-01-23 | — | — | EP | disclosed |