Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 6/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.46 |
| ▸ | CDC25B | P30305 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22456033 | 0.85 | KAT2B (0.61) | HCAR3HTTMAPTTDP1L3MBTL1 | |
| SCHEMBL9458424 | 0.83 | HCAR3 (0.58) | HCAR3HTTMAPTTDP1L3MBTL1 | |
| SCHEMBL10039064 | 0.83 | HCAR3 (0.50) | HCAR3HTTMAPTTDP1L3MBTL1 | |
| SCHEMBL1492448 | 0.77 | ALDH1A1 (0.55) | HTTMAPTTSHRALDH1A1MAPK1 | |
| SCHEMBL1982270 | 0.77 | L3MBTL1 (0.61) | HCAR3HTTMAPTTDP1L3MBTL1 | |
| SCHEMBL22115089 | 0.77 | HCAR3 (0.55) | HCAR3HTTMAPTTDP1L3MBTL1 | |
| SCHEMBL7483108 | 0.77 | HCAR3 (0.58) | HCAR3HTTMAPTTDP1CDC25B | |
| SCHEMBL2319014 | 0.76 | MAPT (0.56) | HCAR3HTTMAPTTDP1L3MBTL1 | |
| SCHEMBL365880 | 0.75 | MAPT (0.60) | HCAR3HTTMAPTTDP1L3MBTL1 | |
| SCHEMBL10534498 | 0.75 | HTT (0.71) | HCAR3HTTMAPTTDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5258370-A | Artificial redox enzymes | CURATORS OF THE UNIVERSITY OF MISSOURI (US) | 1993-11-02 | — | — | US | disclosed |
| WO-1992017508-A1 | ARTIFICIAL REDOX ENZYMES | UNIVERSITY OF MISSOURI (US) | 1992-10-15 | — | — | WO | disclosed |