Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 18/20 | 0.42 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.38 |
| ▸ | HTR1D | P28221 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9458357 | 0.84 | ALOX5 (0.41) | ALOX5HTR1D | |
| SCHEMBL9458197 | 0.81 | SLC6A4 (0.35) | ALOX5OPRL1 | |
| SCHEMBL9458201 | 0.81 | OPRL1 (0.43) | ALOX5OPRL1 | |
| SCHEMBL9380811 | 0.80 | ALOX5 (0.61) | ALOX5 | |
| SCHEMBL1598843 | 0.76 | ALOX5 (0.44) | ALOX5HTR1D | |
| SCHEMBL1599986 | 0.76 | ALOX5 (0.38) | ALOX5HTR1D | |
| SCHEMBL9084952 | 0.76 | MAP2K2 (0.34) | ALOX5 | |
| SCHEMBL1598884 | 0.76 | RECQL (0.37) | ALOX5 | |
| SCHEMBL9268618 | 0.76 | ALOX5 (0.42) | ALOX5 | |
| SCHEMBL9084888 | 0.75 | PTPN11 (0.34) | ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5208259-A | Lipoxygenase enzyme inhibitors | IMPERIAL CHEMICAL INDUSTRIES (GB) | 1993-05-04 | — | — | US | disclosed |
| EP-0409413-A2 | Diaryl ether heterocycles | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-01-23 | — | — | EP | disclosed |