Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 14/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.33 |
| ▸ | HTR1D | P28221 | 1/20 | 0.32 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.32 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.32 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9458201 | 0.84 | OPRL1 (0.43) | ALOX5SMN1; SMN2 | |
| SCHEMBL9458188 | 0.84 | ALOX5 (0.42) | ALOX5HTR1D | |
| SCHEMBL9458222 | 0.79 | ALOX5 (0.36) | ALOX5LMNA | |
| SCHEMBL9458668 | 0.78 | CYP1A2 (0.34) | ALOX5CYP1A2CYP2A6 | |
| SCHEMBL9381681 | 0.78 | CYP1A2 (0.32) | CYP1A2CYP2A6PTPN11SIRT2SIRT1 | |
| SCHEMBL9458568 | 0.78 | ALOX5 (0.48) | ALOX5SMN1; SMN2 | |
| SCHEMBL9367759 | 0.75 | ALOX5 (0.39) | ALOX5 | |
| SCHEMBL9221371 | 0.75 | ALOX5 (0.68) | ALOX5 | |
| SCHEMBL9268918 | 0.75 | ALOX5 (0.45) | ALOX5 | |
| SCHEMBL7479848 | 0.74 | HDAC3 (0.43) | ALOX5HDAC3HDAC1HDAC2HTR1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5208259-A | Lipoxygenase enzyme inhibitors | IMPERIAL CHEMICAL INDUSTRIES (GB) | 1993-05-04 | — | — | US | disclosed |
| EP-0409413-A2 | Diaryl ether heterocycles | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-01-23 | — | — | EP | disclosed |