Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 5/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 7/20 | 0.33 |
| ▸ | SYK | P43405 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9458357 | 0.84 | ALOX5 (0.41) | ALOX5SMN1; SMN2 | |
| SCHEMBL9380828 | 0.83 | ALOX5 (0.47) | ALOX5 | |
| SCHEMBL9458188 | 0.81 | ALOX5 (0.42) | OPRL1ALOX5 | |
| SCHEMBL9458313 | 0.79 | OPRL1 (0.43) | OPRL1ALOX5SLC6A2SLC6A4 | |
| SCHEMBL9458108 | 0.78 | ALOX5 (0.34) | OPRL1OPRM1MAPTKDM4EALDH1A1 | |
| SCHEMBL9458637 | 0.78 | ALOX5 (0.32) | OPRL1ALOX5SYKSMN1; SMN2 | |
| SCHEMBL9458418 | 0.77 | MAP3K12 (0.35) | OPRL1OPRM1ALDH1A1SYKNPC1 | |
| SCHEMBL9221998 | 0.71 | OPRL1 (0.35) | OPRL1OPRM1ALOX5SYKOPRD1 | |
| SCHEMBL9224526 | 0.71 | ALOX5 (0.47) | ALOX5 | |
| SCHEMBL9458604 | 0.70 | CYP2A6 (0.40) | MAPTKDM4EALDH1A1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5208259-A | Lipoxygenase enzyme inhibitors | IMPERIAL CHEMICAL INDUSTRIES (GB) | 1993-05-04 | — | — | US | disclosed |
| EP-0409413-A2 | Diaryl ether heterocycles | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-01-23 | — | — | EP | disclosed |