Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8139163 | 1.00 | HTR1A (0.49) | HTR1ADRD2 | |
| SCHEMBL8139159 | 1.00 | HTR1A (0.49) | HTR1ADRD2 | |
| SCHEMBL8139177 | 1.00 | HTR1A (0.49) | HTR1ADRD2 | |
| Hydrochloric Acid SCHEMBL9458094 | 0.99 | HTR1A (0.48) | HTR1ADRD2 | |
| Hydrochloric Acid SCHEMBL8139068 | 0.99 | HTR1A (0.48) | HTR1ADRD2 | |
| Hydrochloric Acid SCHEMBL9458091 | 0.99 | HTR1A (0.48) | HTR1ADRD2 | |
| Hydrochloric Acid SCHEMBL7848915 | 0.99 | HTR1A (0.48) | HTR1ADRD2 | |
| Hydrochloric Acid SCHEMBL9458086 | 0.99 | HTR1A (0.48) | HTR1ADRD2 | |
| Hydrochloric Acid SCHEMBL10836791 | 0.81 | ADRA1A (0.56) | — | |
| SCHEMBL8136238 | 0.79 | HSD11B1 (0.59) | HTR1ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5244888-A | Hexahydroindenopyrroles and hexahydrobenzisoindoles | ABBOTT LABORATORIES (US) | 1993-09-14 | — | — | US | disclosed |
| US-5049564-A | Hypotensive, 5-hydroxytryptamine | ABBOTT LABORATORIES (US) | 1991-09-17 | — | — | US | disclosed |
| EP-0422134-A1 | 5-HT SELECTIVE AGENTS. | ABBOTT LAB (US) | 1991-04-17 | — | — | EP | disclosed |
| WO-1990006927-A1 | 5-HT SELECTIVE AGENTS | ABBOTT LABORATORIES (US) | 1990-06-28 | — | — | WO | disclosed |