Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.36 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11451929 | 0.91 | TSHR (0.37) | TSHR | |
| SCHEMBL751259 | 0.84 | TSHR (0.41) | TSHRGRIN1GRIN2ACHRM2CHRM4 | |
| SCHEMBL11451919 | 0.83 | SLC6A2 (0.36) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL28603091 | 0.79 | GRIN1 (0.43) | GRIN1GRIN2ACHRM2CHRM4CHRM1 | |
| SCHEMBL28599785 | 0.79 | GRIN1 (0.43) | GRIN1GRIN2ACHRM2CHRM4CHRM1 | |
| SCHEMBL11463719 | 0.78 | THRB (0.39) | — | |
| SCHEMBL2109364 | 0.77 | HTR1A (0.39) | — | |
| SCHEMBL11454301 | 0.77 | CYP3A4 (0.40) | TSHRSLC6A4SLC6A3 | |
| SCHEMBL12132792 | 0.76 | GRIN1 (0.36) | GRIN1GRIN2ACHRM2CHRM4CHRM1 | |
| SCHEMBL12132793 | 0.76 | GRIN1 (0.36) | GRIN1GRIN2ACHRM2CHRM4CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5266585-A | Controlling phytopathogenic microorganisms, fungicides, antimycotics, anticonvulsives and/or anxiolytic agents | CIBA-GEIGY CORPORATION (US) | 1993-11-30 | — | — | US | disclosed |
| EP-0443980-A1 | Microbicidal agents | CIBA-GEIGY AG (CH) | 1991-08-28 | — | — | EP | disclosed |
| EP-0215307-B1 | PYRIMIDIN DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS MICROBICIDES | CIBA-GEIGY AG (CH) | 1991-07-24 | — | — | EP | disclosed |
| US-4940806-A | Microbicides | CIBA-GEIGY CORPORATION (US) | 1990-07-10 | — | — | US | disclosed |
| EP-0065485-B1 | ARYLPHENYL ETHER DERIVATIVES AS MICROBICIDES, PROCESS FOR THEIR PREPARATION AND THEIR APPLICATION | CIBA-GEIGY AG (CH) | 1990-04-18 | — | — | EP | disclosed |
| US-4859687-A | Substituted 1,3-dioxolane compounds and their use as fungicides | CIBA-GIEGY CORPORATION (US) | 1989-08-22 | — | — | US | disclosed |
| US-4853399-A | Microbicidal triazolyl phenylethanone ketals | CIBA-GEIGY CORPORATION (US) | 1989-08-01 | — | — | US | disclosed |
| EP-0129507-B1 | MICROBICIDES | CIBA-GEIGY AG (CH) | 1989-02-01 | — | — | EP | disclosed |
| EP-0296518-A1 | Phenyl-ether derivatives, process for their preparation and application | CIBA-GEIGY AG (CH) | 1988-12-28 | — | — | EP | disclosed |
| US-4727075-A | Fungicidal 5-substituted pyrimidine derivatives, compositions, and method of use therefor | CIBA-GEIGY CORPORATION (US) | 1988-02-23 | — | — | US | disclosed |
| US-4156008-A | FUNGICIDES, BACTERICIDES | JANSSEN PHARMACEUTICA N.V. (BE) | 1979-05-22 | — | — | US | disclosed |
| US-4154738-A | 1-(2-AR-4-ARYLOXYMETHYL-1,3-DIOXOLAN-2-YL-METHYL)-IMIDAZOLES, FUNGICIDES, BACTERICIDES | JANSSEN PHARMACEUTICA N.V. (BE) | 1979-05-15 | — | — | US | disclosed |
| US-4141908-A | FUNGICIDES, BACTERICIDES | JANSSEN PHARMACEUTICA N.V. (BE) | 1979-02-27 | — | — | US | disclosed |
| US-4139540-A | FUNGICIDE, BACTERICIDE INTERMEDIATE | JANSSEN PHARMACEUTICA N.V. (BE) | 1979-02-13 | — | — | US | disclosed |
| US-4120869-A | FUNGICIDES, BACTERICIDES | JANSSEN PHARMACEUTICA N.V. (BE) | 1978-10-17 | — | — | US | disclosed |
| US-4119641-A | ANTIFUNGAL, ANTIBACTERIAL AGENTS | JANSSEN PHARMACEUTICA N.V. (BE) | 1978-10-10 | — | — | US | disclosed |
| US-4101665-A | FUNGICIDES, BACTERICIDES | JANSSEN PHARMACEUTICA N.V. (BE) | 1978-07-18 | — | — | US | disclosed |
| US-4101664-A | FUNGICIDES, BACTERICIDES | JANSSEN PHARMACEUTICA N.V. (BE) | 1978-07-18 | — | — | US | disclosed |
| US-4101666-A | FUNGICIDES, BACTERICIDES | JANSSEN PHARMACEUTICA N.V. (BE) | 1978-07-18 | — | — | US | disclosed |
| US-3936470-A | FUNGICIDES, BACTERICIDES | JANSSEN PHARMACEUTICA N.V. (BE) | 1976-02-03 | — | — | US | disclosed |