SCHEMBL2109364

SCHEMBL2109364

c1ccc(C2COC(CN3CCCCC3)(c3ccccc3)O2)cc1

nearest known ligand 0.39

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
HTR1A P08908 10/20 0.39
ADRA1D P25100 10/20 0.39
ADRA1A P35348 10/20 0.39
ADRA1B P35368 10/20 0.39
LTA4H P09960 4/20 0.37
HRH1 P35367 1/20 0.37
HRH3 Q9Y5N1 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Iodide SCHEMBL663030 0.99 HTR1A (0.38) HTR1AADRA1DADRA1AADRA1BLTA4H
SCHEMBL751259 0.77 TSHR (0.41)
SCHEMBL9458455 0.77 TSHR (0.41)
SCHEMBL11451929 0.69 TSHR (0.37)
SCHEMBL11452742 0.69 ADRA1A (0.47) ADRA1A
SCHEMBL16973469 0.65 TSHR (0.45)
SCHEMBL10759760 0.65 TMEM97 (0.49) HTR1AADRA1DADRA1AADRA1B
SCHEMBL25197896 0.65 SIGMAR1 (0.64) HTR1AADRA1DADRA1AADRA1BLTA4H
Hydrochloric Acid SCHEMBL30904664 0.64 HTR1A (0.67) HTR1AADRA1DADRA1AADRA1B
SCHEMBL6888254 0.63 SLC6A4 (0.59)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9016221-B2 Surface topographies for non-toxic bioadhesion control UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2015-04-28 US claimed
US-20100226943-A1 SURFACE TOPOGRAPHIES FOR NON-TOXIC BIOADHESION CONTROL UNIVERSITY OF FLORIDA (US) 2010-09-09 US claimed
CN-101330905-A Freeze-drying process and products obtained thereby SCIDOSE LLC (US) 2008-12-24 CN claimed
EP-1954244-A1 LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY Scidose, Llc (US) 2008-08-13 EP claimed
WO-2007061529-A1 LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY SCIDOSE LLC. (US) 2007-05-31 WO claimed
US-20070116729-A1 Lyophilization process and products obtained thereby SCIDOSE LLC 2007-05-24 US claimed
US-20220047505-A1 Controlled Absorption Water-Soluble Pharmaceutically Active Organic Compound Formulation for Once-Daily Administration STI PHARMA, LLC (US) 2022-02-17 US disclosed
US-11191719-B2 Controlled absorption water-soluble pharmaceutically active organic compound formulation for once-daily administration STI PHARMA, LLC (US) 2021-12-07 US disclosed
US-10471140-B2 Composition for enhancing induction of humoral immunity, and vaccine pharmaceutical composition NOTTO DENKO CORPORATION (JP) 2019-11-12 US disclosed
US-10463611-B2 Controlled absorption water-soluble pharmaceutically active organic compound formulation for once-daily administration STI PHARMA, LLC (US) 2019-11-05 US disclosed
US-20190298825-A1 COMPOSITION FOR ENHANCING INDUCTION OF HUMORAL IMMUNITY, AND VACCINE PHARMACEUTICAL COMPOSITION NITTO DENKO CORPORATION (JP) 2019-10-03 US disclosed
US-10369219-B2 Composition for enhancing induction of humoral immunity, and vaccine pharmaceutical composition NITTO DENKO CORPORATION (JP) 2019-08-06 US disclosed
US-10286067-B2 2019-05-14 US disclosed
US-7905852-B2 Skin-contacting-adhesive free dressing JENNINGS-SPRING BARBARA 2011-03-15 US disclosed
US-20100226943-A1 SURFACE TOPOGRAPHIES FOR NON-TOXIC BIOADHESION CONTROL UNIVERSITY OF FLORIDA (US) 2010-09-09 US disclosed
WO-2010024870-A1 SKIN-CONTACTING-ADHESIVE FREE DRESSING JENNINGS-SPRING BARBARA BROOKE (US) 2010-03-04 WO disclosed
US-20090005722-A1 Skin-contacting-adhesive free dressing JENNLNGS-SPRING BARBARA 2009-01-01 US disclosed
EP-1954244-A1 LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY Scidose, Llc (US) 2008-08-13 EP disclosed
WO-2007061529-A1 LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY SCIDOSE LLC. (US) 2007-05-31 WO disclosed
US-20070116729-A1 Lyophilization process and products obtained thereby SCIDOSE LLC 2007-05-24 US disclosed