Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | PRNP | P04156 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 7/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9458374 | 0.84 | MAPT (0.43) | KDM4EHSD17B10LMNAALDH1A1MEN1 | |
| SCHEMBL13214422 | 0.82 | KDM4E (0.47) | KDM4EHSD17B10LMNAALDH1A1MEN1 | |
| SCHEMBL9458139 | 0.81 | APP (0.43) | KDM4EHSD17B10LMNAALDH1A1MEN1 | |
| SCHEMBL29923763 | 0.81 | KDM4E (0.46) | KDM4EHSD17B10LMNAALDH1A1MEN1 | |
| SCHEMBL9680806 | 0.80 | ALDH1A1 (0.40) | KDM4EHSD17B10LMNAALDH1A1MEN1 | |
| SCHEMBL9458592 | 0.78 | DHODH (0.43) | KDM4EALDH1A1MEN1KMT2APRNP | |
| SCHEMBL9458576 | 0.78 | ESR1 (0.51) | KDM4EHSD17B10ALDH1A1MEN1KMT2A | |
| SCHEMBL9458597 | 0.78 | KDM4E (0.44) | KDM4EALDH1A1KMT2APOLBGAA | |
| SCHEMBL9458599 | 0.75 | ALDH1A1 (0.37) | KDM4ELMNAALDH1A1MEN1KMT2A | |
| SCHEMBL9458614 | 0.75 | TYMS (0.39) | KDM4EHSD17B10LMNAALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5245035-A | HETEROCYCLIC BORON COMPOUNDS AS INTERMEDIATES FOR ANGIOTENSIN II ANTAGONISTS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-09-14 | — | — | US | claimed |
| EP-0495627-A1 | Boron compounds | ZENECA LIMITED (GB) | 1992-07-22 | — | — | EP | claimed |
| US-5245035-A | HETEROCYCLIC BORON COMPOUNDS AS INTERMEDIATES FOR ANGIOTENSIN II ANTAGONISTS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-09-14 | — | — | US | disclosed |
| EP-0495627-A1 | Boron compounds | ZENECA LIMITED (GB) | 1992-07-22 | — | — | EP | disclosed |