Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.42 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | PRNP | P04156 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9458485 | 0.84 | KDM4E (0.50) | MAPTALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL9458139 | 0.78 | APP (0.43) | MAPTPDE3BPDE3AALDH1A1KDM4E | |
| SCHEMBL9680806 | 0.77 | ALDH1A1 (0.40) | TP53ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL7837270 | 0.76 | PDE3B (0.49) | MAPTTP53PDE3BPDE3AALDH1A1 | |
| SCHEMBL9458576 | 0.74 | ESR1 (0.51) | ALDH1A1KDM4EHPGDHSD17B10KMT2A | |
| SCHEMBL9458592 | 0.74 | DHODH (0.43) | MAPTALDH1A1KDM4EHPGDTSHR | |
| SCHEMBL9458599 | 0.72 | ALDH1A1 (0.37) | MAPTALDH1A1KDM4EHPGDCYP1A2 | |
| SCHEMBL9458614 | 0.72 | TYMS (0.39) | MAPTALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL9273904 | 0.72 | KDM4E (0.47) | MAPTALDH1A1KDM4EHPGDCYP1A2 | |
| SCHEMBL2511086 | 0.69 | KMT2A (0.45) | MAPTTP53ALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5245035-A | HETEROCYCLIC BORON COMPOUNDS AS INTERMEDIATES FOR ANGIOTENSIN II ANTAGONISTS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-09-14 | — | — | US | claimed |
| EP-0495626-A1 | Process for the preparation of tetrazole derivatives | ZENECA LIMITED (GB) | 1992-07-22 | — | — | EP | claimed |
| EP-0495627-A1 | Boron compounds | ZENECA LIMITED (GB) | 1992-07-22 | — | — | EP | claimed |
| US-5245035-A | HETEROCYCLIC BORON COMPOUNDS AS INTERMEDIATES FOR ANGIOTENSIN II ANTAGONISTS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-09-14 | — | — | US | disclosed |
| EP-0495627-A1 | Boron compounds | ZENECA LIMITED (GB) | 1992-07-22 | — | — | EP | disclosed |