Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 3/20 | 0.43 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | TYMS | P04818 | 1/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PRNP | P04156 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 3/20 | 0.37 |
| ▸ | TNKS | O95271 | 2/20 | 0.37 |
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.37 |
| ▸ | MPO | P05164 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9458576 | 0.80 | ESR1 (0.51) | ALDH1A1GAAMEN1HPGDKMT2A | |
| SCHEMBL9458485 | 0.78 | KDM4E (0.50) | PLA2G2ATSHRALDH1A1GAAMEN1 | |
| SCHEMBL9458599 | 0.78 | ALDH1A1 (0.37) | TYMSTSHRALDH1A1GAAMEN1 | |
| SCHEMBL26317683 | 0.78 | PDE10A (0.53) | DHODHPLA2G2APDE10AMEN1KMT2A | |
| SCHEMBL9458614 | 0.78 | TYMS (0.39) | DHODHTYMSTSHRALDH1A1GAA | |
| SCHEMBL9273904 | 0.77 | KDM4E (0.47) | ALDH1A1GAAMEN1HPGDKMT2A | |
| SCHEMBL9458139 | 0.75 | APP (0.43) | TSHRALDH1A1MEN1HPGDKMT2A | |
| SCHEMBL9458481 | 0.74 | CCNE2 (0.44) | ALDH1A1POLB | |
| SCHEMBL9458374 | 0.74 | MAPT (0.43) | TSHRALDH1A1GAAMEN1HPGD | |
| SCHEMBL9680806 | 0.74 | ALDH1A1 (0.40) | TYMSTSHRALDH1A1MEN1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5245035-A | HETEROCYCLIC BORON COMPOUNDS AS INTERMEDIATES FOR ANGIOTENSIN II ANTAGONISTS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-09-14 | — | — | US | claimed |
| EP-0495627-A1 | Boron compounds | ZENECA LIMITED (GB) | 1992-07-22 | — | — | EP | claimed |
| US-5245035-A | HETEROCYCLIC BORON COMPOUNDS AS INTERMEDIATES FOR ANGIOTENSIN II ANTAGONISTS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-09-14 | — | — | US | disclosed |
| EP-0495627-A1 | Boron compounds | ZENECA LIMITED (GB) | 1992-07-22 | — | — | EP | disclosed |