Hesperidin

Hesperidin

SCHEMBL94586

COc1ccc([C@@H]2CC(=O)c3c(O)cc(O[C@@H]4O[C@H](CO[C@@H]5O[C@@H](C)[C@H](O)[C@@H](O)[C@H]5O)[C@@H](O)[C@H](O)[C@H]4O)cc3O2)cc1O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KDM1A O60341 4/20 1.00
▸ GSK3B P49841 3/20 1.00
▸ MEN1 O00255 3/20 1.00
▸ KMT2A Q03164 3/20 1.00
▸ POLB P06746 2/20 1.00
▸ TDP1 Q9NUW8 2/20 1.00
▸ CALM1 P0DP23 1/20 1.00
▸ CACNA1B Q00975 1/20 1.00
▸ APBA1 Q02410 1/20 1.00
▸ CTDSP1 Q9GZU7 1/20 1.00
▸ DPP4 P27487 2/20 0.85
▸ PTPN1 P18031 3/20 0.83
▸ PKM P14618 2/20 0.65
▸ SLCO2B1 O94956 2/20 0.64
▸ SYNJ2 O15056 1/20 0.64
▸ CYP19A1 P11511 3/20 0.62
▸ UBE2N P61088 1/20 0.62
▸ TP53 P04637 3/20 0.59
▸ ALDH1A1 P00352 2/20 0.59
▸ KDM4E B2RXH2 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hesperidin SCHEMBL17849327 1.00 KDM1A (1.00) KDM1AGSK3BMEN1KMT2APOLB
Hesperidin SCHEMBL17849125 1.00 KDM1A (1.00) KDM1AGSK3BMEN1KMT2APOLB
Hesperidin SCHEMBL4450832 1.00 KDM1A (1.00) KDM1AGSK3BMEN1KMT2APOLB
Hesperidin SCHEMBL15214210 1.00 KDM1A (1.00) KDM1AGSK3BMEN1KMT2APOLB
Hesperidin SCHEMBL765367 1.00 KDM1A (1.00) KDM1AGSK3BMEN1KMT2APOLB
Hesperidin SCHEMBL8018716 1.00 KDM1A (1.00) KDM1AGSK3BMEN1KMT2APOLB
Hesperidin SCHEMBL24105886 1.00 KDM1A (1.00) KDM1AGSK3BMEN1KMT2APOLB
Hesperidin SCHEMBL3764160 1.00 KDM1A (1.00) KDM1AGSK3BMEN1KMT2APOLB
Hesperidin SCHEMBL18654117 1.00 KDM1A (1.00) KDM1AGSK3BMEN1KMT2APOLB
Hesperidin SCHEMBL22946699 1.00 KDM1A (1.00) KDM1AGSK3BMEN1KMT2APOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 23961 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4748368-A1 COMPOSITION FOR ORAL HYGIENE PRODUCTS COMPRISING N-CETYLPYRIDINIUM CHLORIDE, A FLAVONOID AND A POLYMER Curaden AG (CH) 2026-05-27 — — EP claimed
CN-122080093-A Compounds effective in treating liver toxicity and fatty liver disease and uses thereof — 2026-05-26 — — CN claimed
CN-122080096-A Preparation method and application of diosmin impurity compound — 2026-05-26 — — CN claimed
CN-121476492-B Fingerprint spectrum determination method for chicken's gizzard-membrane and chrysanthemum mixed plant solid beverage Yabao Jiuhe (Beijing) Health Technology Co.,Ltd. (CN) 2026-05-26 — — CN claimed
US-12636251-B1 Glycoside-containing aqueous formulations having a lipophilic active component Doane Technology Group LLC (US) 2026-05-26 — — US claimed
CN-117959202-B Composition for inhibiting photodegradation of ergothioneine based on glucosyl hesperidin Shanghai Jahwa United Co.,Ltd. (CN) 2026-05-26 — — CN claimed
CN-121914965-B Serum-free culture medium for proliferation of bovine muscle stem cells and application thereof NANJING AGRICULTURAL UNIVERSITY (CN) 2026-05-26 — — CN claimed
CN-122074524-A Embedding and aroma-locking process for dried orange peel flavor bread — 2026-05-26 — — CN claimed
CN-122075559-A Portulaca oleracea extract based on bioaffinity ultrafiltration screening and preparation method and application thereof — 2026-05-26 — — CN claimed
CN-122094662-A Lime (citrus aurantium) extracts and their use as cosmetic agents — 2026-05-26 — — CN claimed
US-4496548-A Composition and method for reducing hangover MOLDOWAN MERVIN J 1985-01-29 — — US claimed
EP-0123296-A1 Use of hesperidine Blendax-Werke R. Schneider GmbH & Co. (DE) 1984-10-31 — — EP claimed
US-4334020-A Method of producing L-glutamic acid by fermentation AJINOMOTO COMPANY INCORPORATED (JP) 1982-06-08 — — US claimed
EP-0052086-A1 Process for producing flavone derivatives with medicinal activity BONOMELLI S.p.A. (IT) 1982-05-19 — — EP claimed
US-4238483-A Antimicrobial compositions of matter and a process for preparing antimicrobial compositions of matter from naturally occurring flavanoid glycosides RUSH-HAMPTON INDUSTRIES, INC. 1980-12-09 — — US claimed
US-4211772-A CAPILLARIES, DIABETIC CATARACTS LABORATOIRES SARGET (FR) 1980-07-08 — — US claimed
EP-0010108-A1 Stabilized prostaglandine E composition TORAY INDUSTRIES, INC. (JP) 1980-04-30 — — EP claimed
US-4178454-A WITH METHYLHESPERIDIN TORAY INDUSTRIES, INC. (JP) 1979-12-11 — — US claimed
US-4150038-A Conversion of hesperidin into hesperetin DYNAPOL (US) 1979-04-17 — — US claimed
US-4078137-A Process for manufacturing a flavone derivative HOMMEL AKTIENGESELLSCHAFT (CH) 1978-03-07 — — US claimed
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