Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 4/20 | 1.00 |
| ▸ | GSK3B | P49841 | 3/20 | 1.00 |
| ▸ | MEN1 | O00255 | 3/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 3/20 | 1.00 |
| ▸ | POLB | P06746 | 2/20 | 1.00 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 1.00 |
| ▸ | CALM1 | P0DP23 | 1/20 | 1.00 |
| ▸ | CACNA1B | Q00975 | 1/20 | 1.00 |
| ▸ | APBA1 | Q02410 | 1/20 | 1.00 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 1.00 |
| ▸ | DPP4 | P27487 | 2/20 | 0.85 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.83 |
| ▸ | PKM | P14618 | 2/20 | 0.65 |
| ▸ | SLCO2B1 | O94956 | 2/20 | 0.64 |
| ▸ | SYNJ2 | O15056 | 1/20 | 0.64 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.62 |
| ▸ | UBE2N | P61088 | 1/20 | 0.62 |
| ▸ | TP53 | P04637 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hesperidin SCHEMBL17849327 | 1.00 | KDM1A (1.00) | KDM1AGSK3BMEN1KMT2APOLB | |
| Hesperidin SCHEMBL17849125 | 1.00 | KDM1A (1.00) | KDM1AGSK3BMEN1KMT2APOLB | |
| Hesperidin SCHEMBL4450832 | 1.00 | KDM1A (1.00) | KDM1AGSK3BMEN1KMT2APOLB | |
| Hesperidin SCHEMBL15214210 | 1.00 | KDM1A (1.00) | KDM1AGSK3BMEN1KMT2APOLB | |
| Hesperidin SCHEMBL8018716 | 1.00 | KDM1A (1.00) | KDM1AGSK3BMEN1KMT2APOLB | |
| Hesperidin SCHEMBL24105886 | 1.00 | KDM1A (1.00) | KDM1AGSK3BMEN1KMT2APOLB | |
| Hesperidin SCHEMBL3764160 | 1.00 | KDM1A (1.00) | KDM1AGSK3BMEN1KMT2APOLB | |
| Hesperidin SCHEMBL18654117 | 1.00 | KDM1A (1.00) | KDM1AGSK3BMEN1KMT2APOLB | |
| Hesperidin SCHEMBL22946699 | 1.00 | KDM1A (1.00) | KDM1AGSK3BMEN1KMT2APOLB | |
| Hesperidin SCHEMBL94586 | 1.00 | KDM1A (1.00) | KDM1AGSK3BMEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11453694-B2 | Glycosyl hesperetin and process for producing the same and uses thereof | HAYASHIBARA CO. LTD. (JP) | 2022-09-27 | — | — | US | disclosed |
| US-20220062318-A1 | HEAT STRESS RELIEVING AGENT | Hayashibara Co., Ltd. (JP) | 2022-03-03 | — | — | US | disclosed |
| US-20200283466-A1 | GLYCOSYL HESPERETIN AND PROCESS FOR PRODUCING THE SAME AND USES THEREOF | NAGASE VIITA CO., LTD. (JP) | 2020-09-10 | — | — | US | disclosed |
| US-10568827-B2 | External dermal agent for reducing yellowish dullness | Hayashibara Co., Ltd. (JP) | 2020-02-25 | — | — | US | disclosed |
| US-9415034-B2 | Inhibitors and enhancers of uridine diphosphate-glucuronosyltransferase 2B (UGT2B) | NATIONAL DEFENSE MEDICAL CENTER (TW) | 2016-08-16 | — | — | US | disclosed |
| US-9415034-B2 | Inhibitors and enhancers of uridine diphosphate-glucuronosyltransferase 2B (UGT2B) | NATIONAL DEFENSE MEDICAL CENTER (TW) | 2016-08-16 | — | — | US | disclosed |
| US-20160184298-A1 | INHIBITORS AND ENHANCERS OF URIDINE DIPHOSPHATE-GLUCURONOSYLTRANSFERASE 2B (UGT2B) | NAT DEFENSE MEDICAL CT (TW) | 2016-06-30 | — | — | US | disclosed |
| US-20160184298-A1 | INHIBITORS AND ENHANCERS OF URIDINE DIPHOSPHATE-GLUCURONOSYLTRANSFERASE 2B (UGT2B) | NAT DEFENSE MEDICAL CT (TW) | 2016-06-30 | — | — | US | disclosed |
| US-8227426-B2 | Chiral complexes of ascorbic acid with natural antioxidant and anti-inflammatory ketones including aloe, citrus, ginger, and mango for skin and hair care | ISLAND KINETICS INC. (US) | 2012-07-24 | — | — | US | disclosed |
| EP-2017272-B1 | Method to release certain flavanons and dihydrochalcones using acid hydrolysis | SYMRISE AG (DE) | 2012-03-21 | — | — | EP | disclosed |
| US-7759317-B2 | Analgesic and anti-inflammatory compositions and methods with flavonoid glycoside-type compounds | BMB PATENT HOLDING CORPORATION (US) | 2010-07-20 | — | — | US | disclosed |
| US-7759317-B2 | Analgesic and anti-inflammatory compositions and methods with flavonoid glycoside-type compounds | BMB PATENT HOLDING CORPORATION (US) | 2010-07-20 | — | — | US | disclosed |
| US-20090074708-A1 | Inhibitors and Enhancers of Uridine Diphosphate-Glucuronosyltransferase 2B (UGT2B) | NATIONAL DEFENSE MEDICAL UNIVERSITY (TW) | 2009-03-19 | — | — | US | disclosed |
| US-20090074708-A1 | Inhibitors and Enhancers of Uridine Diphosphate-Glucuronosyltransferase 2B (UGT2B) | NATIONAL DEFENSE MEDICAL UNIVERSITY (TW) | 2009-03-19 | — | — | US | disclosed |
| EP-2017272-A2 | Method to release certain flavanons and dihydrochalcones using acid hydrolysis | Symrise GmbH & Co. KG (DE) | 2009-01-21 | — | — | EP | disclosed |
| US-20080267948-A1 | Croos-B Structure Binding Compounds | CROSSBETA BIOSCIENCES B.V. (NL) | 2008-10-30 | — | — | US | disclosed |
| US-20080267948-A1 | Croos-B Structure Binding Compounds | CROSSBETA BIOSCIENCES B.V. (NL) | 2008-10-30 | — | — | US | disclosed |
| US-20080171708-A1 | ANALGESIC AND ANTI-INFLAMMATORY COMPOSITIONS AND METHODS WITH FLAVONOID GLYCOSIDE-TYPE COMPOUNDS | BMB PATENT HOLDING CORPORATION (US) | 2008-07-17 | — | — | US | disclosed |
| US-20080171708-A1 | ANALGESIC AND ANTI-INFLAMMATORY COMPOSITIONS AND METHODS WITH FLAVONOID GLYCOSIDE-TYPE COMPOUNDS | BMB PATENT HOLDING CORPORATION (US) | 2008-07-17 | — | — | US | disclosed |
| WO-2008083332-A1 | ANALGESIC AND ANTI-INFLAMMATORY COMPOSITIONS AND METHODS WITH FLAVONOID GLYCOSIDE -TYPE COMPOUNDS | BMB PATENT HOLDING CORPORATION (US) | 2008-07-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200283466-A1 | GLYCOSYL HESPERETIN AND PROCESS FOR PRODUCING THE SAME AND USES THEREOF | HES1, DHPS, UGGT1 | KDM1A 858/4885GSK3B 4288/4885MEN1 805/4885 |
| US-20080267948-A1 | Croos-B Structure Binding Compounds | CACYBP, TBCB, MYCBP | KDM1A 4583/4885GSK3B 155/4885MEN1 4546/4885 |
| US-11453694-B2 | Glycosyl hesperetin and process for producing the same and uses thereof | HES1, DHPS, UGGT1 | KDM1A 858/4885GSK3B 4288/4885MEN1 805/4885 |
| US-20160184298-A1 | INHIBITORS AND ENHANCERS OF URIDINE DIPHOSPHATE-GLUCURONOSYLTRANSFERASE 2B (UGT2B) | UGT2B7, UGT2B17, UGT1A10 | KDM1A 4671/4885GSK3B 1828/4885MEN1 4841/4885 |
| US-20220062318-A1 | HEAT STRESS RELIEVING AGENT | HSF1, HEATR1, HSPA2 | KDM1A 2976/4885GSK3B 4011/4885MEN1 2867/4885 |
| US-20080171708-A1 | ANALGESIC AND ANTI-INFLAMMATORY COMPOSITIONS AND METHODS WITH FLAVONOID GLYCOSIDE-TYPE COMPOUNDS | PTGS1, PTGS2, PTGES | KDM1A 2812/4885GSK3B 1693/4885MEN1 4859/4885 |
| US-10568827-B2 | External dermal agent for reducing yellowish dullness | FUT5, ENGASE, FUT6 | KDM1A 954/4885GSK3B 2886/4885MEN1 4298/4885 |
| US-20090074708-A1 | Inhibitors and Enhancers of Uridine Diphosphate-Glucuronosyltransferase 2B (UGT2B) | UGT2B7, UGT2B17, UGT1A10 | KDM1A 4671/4885GSK3B 1828/4885MEN1 4841/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.