Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 4/20 | 1.00 |
| ▸ | GSK3B | P49841 | 3/20 | 1.00 |
| ▸ | MEN1 | O00255 | 3/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 3/20 | 1.00 |
| ▸ | POLB | P06746 | 2/20 | 1.00 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 1.00 |
| ▸ | CALM1 | P0DP23 | 1/20 | 1.00 |
| ▸ | CACNA1B | Q00975 | 1/20 | 1.00 |
| ▸ | APBA1 | Q02410 | 1/20 | 1.00 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 1.00 |
| ▸ | DPP4 | P27487 | 2/20 | 0.85 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.83 |
| ▸ | PKM | P14618 | 2/20 | 0.65 |
| ▸ | SLCO2B1 | O94956 | 2/20 | 0.64 |
| ▸ | SYNJ2 | O15056 | 1/20 | 0.64 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.62 |
| ▸ | UBE2N | P61088 | 1/20 | 0.62 |
| ▸ | TP53 | P04637 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hesperidin SCHEMBL17849327 | 1.00 | KDM1A (1.00) | KDM1AGSK3BMEN1KMT2APOLB | |
| Hesperidin SCHEMBL17849125 | 1.00 | KDM1A (1.00) | KDM1AGSK3BMEN1KMT2APOLB | |
| Hesperidin SCHEMBL4450832 | 1.00 | KDM1A (1.00) | KDM1AGSK3BMEN1KMT2APOLB | |
| Hesperidin SCHEMBL15214210 | 1.00 | KDM1A (1.00) | KDM1AGSK3BMEN1KMT2APOLB | |
| Hesperidin SCHEMBL765367 | 1.00 | KDM1A (1.00) | KDM1AGSK3BMEN1KMT2APOLB | |
| Hesperidin SCHEMBL8018716 | 1.00 | KDM1A (1.00) | KDM1AGSK3BMEN1KMT2APOLB | |
| Hesperidin SCHEMBL24105886 | 1.00 | KDM1A (1.00) | KDM1AGSK3BMEN1KMT2APOLB | |
| Hesperidin SCHEMBL18654117 | 1.00 | KDM1A (1.00) | KDM1AGSK3BMEN1KMT2APOLB | |
| Hesperidin SCHEMBL22946699 | 1.00 | KDM1A (1.00) | KDM1AGSK3BMEN1KMT2APOLB | |
| Hesperidin SCHEMBL94586 | 1.00 | KDM1A (1.00) | KDM1AGSK3BMEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130137767-A1 | Methods and Compositions for Treating Arthritis with Docosahexaenoic Acid | DSM IP ASSETS B.V. (NL) | 2013-05-30 | — | — | US | disclosed |
| US-20100305053-A1 | USE OF HESPERIDIN OR OF A DERIVATIVE THEREOF FOR THE PREVENTION AND/OR TREATMENT OF SLACKENED SKIN | L'OREAL (FR) | 2010-12-02 | — | — | US | disclosed |
| WO-2009031106-A2 | USE OF A COMBINATION OF HESPERIDIN AND OF A MICROORGANISM FOR INFLUENCING THE BARRIER FUNCTION OF THE SKIN | L'OREAL (FR) | 2009-03-12 | — | — | WO | disclosed |
| US-20090068161-A1 | USE OF A COMBINATION OF HESPERIDIN AND OF A MICROORGANISM FOR INFLUENCING THE BARRIER FUNCTION OF THE SKIN | L'OREAL (FR) | 2009-03-12 | — | — | US | disclosed |
| US-20050137253-A1 | Formulations and methods for treatment or amelioration of inflammatory conditions | JOHNSON & JOHNSON CONSUMER INC. | 2005-06-23 | — | — | US | disclosed |
| EP-1517667-A2 | COMPOSITIONS AND METHODS FOR REDUCTION OF INFLAMMATORY SYMPTOMS AND/OR BIOMARKERS IN FEMALE SUBJECTS | Galileo Pharmaceuticals, Inc. (US) | 2005-03-30 | — | — | EP | disclosed |
| US-20040048919-A1 | Compositions and methods for reduction of inflammatory symptoms and/or biomarkers in female subjects | ALLOY VENTURES, INC. | 2004-03-11 | — | — | US | disclosed |
| WO-2004004638-A2 | COMPOSITIONS AND METHODS FOR REDUCTION OF INFLAMMATORY SYMPTOMS AND/OR BIOMARKERS IN FEMALE SUBJECTS | GALILEO PHARMACEUTICALS, INC. (US) | 2004-01-15 | — | — | WO | disclosed |
| WO-2002047680-A9 | USE OF TOCOPHEROL, METABOLITES OR DERIVATIVES THEREOF OR FLAVONOID METABOLITES OR DERIVATIVES THEREOF IN THE MANUFACTURE OF A MEDICAMENT FOR THE TREATMENT OF TISSUE ISCHEMIA | GALILEO LAB INC (US) | 2003-10-09 | — | — | WO | disclosed |
| US-20030144219-A1 | Formulations and methods for treatment or amelioration of inflammatory conditions | JOHNSON & JOHNSON CONSUMER INC. | 2003-07-31 | — | — | US | disclosed |
| US-20030022818-A1 | Formulations of tocopherols and methods of making and using them | ALLOY VENTURES, INC. | 2003-01-30 | — | — | US | disclosed |
| US-20020132845-A1 | Compositions and methods for the prevention and treatment of tissue ischemia | ALLOY VENTURES, INC. | 2002-09-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030144219-A1 | Formulations and methods for treatment or amelioration of inflammatory conditions | ALOX15B, ALOX5, ALOX12 | KDM1A 4825/4885GSK3B 1754/4885MEN1 4579/4885 |
| US-20040048919-A1 | Compositions and methods for reduction of inflammatory symptoms and/or biomarkers in female subjects | PGR, PTGES3, PGRMC1 | KDM1A 4229/4885GSK3B 1355/4885MEN1 3501/4885 |
| US-20050137253-A1 | Formulations and methods for treatment or amelioration of inflammatory conditions | ALOX15B, ALOX5, ALOX12 | KDM1A 4825/4885GSK3B 1754/4885MEN1 4579/4885 |
| US-20020132845-A1 | Compositions and methods for the prevention and treatment of tissue ischemia | NDUFB5, NDUFB3, EBP | KDM1A 4620/4885GSK3B 220/4885MEN1 3915/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.