Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 4/20 | 1.00 |
| ▸ | GSK3B | P49841 | 3/20 | 1.00 |
| ▸ | MEN1 | O00255 | 3/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 3/20 | 1.00 |
| ▸ | POLB | P06746 | 2/20 | 1.00 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 1.00 |
| ▸ | CALM1 | P0DP23 | 1/20 | 1.00 |
| ▸ | CACNA1B | Q00975 | 1/20 | 1.00 |
| ▸ | APBA1 | Q02410 | 1/20 | 1.00 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 1.00 |
| ▸ | DPP4 | P27487 | 2/20 | 0.85 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.83 |
| ▸ | PKM | P14618 | 2/20 | 0.65 |
| ▸ | SLCO2B1 | O94956 | 2/20 | 0.64 |
| ▸ | SYNJ2 | O15056 | 1/20 | 0.64 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.62 |
| ▸ | UBE2N | P61088 | 1/20 | 0.62 |
| ▸ | TP53 | P04637 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hesperidin SCHEMBL17849327 | 1.00 | KDM1A (1.00) | KDM1AGSK3BMEN1KMT2APOLB | |
| Hesperidin SCHEMBL17849125 | 1.00 | KDM1A (1.00) | KDM1AGSK3BMEN1KMT2APOLB | |
| Hesperidin SCHEMBL15214210 | 1.00 | KDM1A (1.00) | KDM1AGSK3BMEN1KMT2APOLB | |
| Hesperidin SCHEMBL765367 | 1.00 | KDM1A (1.00) | KDM1AGSK3BMEN1KMT2APOLB | |
| Hesperidin SCHEMBL8018716 | 1.00 | KDM1A (1.00) | KDM1AGSK3BMEN1KMT2APOLB | |
| Hesperidin SCHEMBL24105886 | 1.00 | KDM1A (1.00) | KDM1AGSK3BMEN1KMT2APOLB | |
| Hesperidin SCHEMBL3764160 | 1.00 | KDM1A (1.00) | KDM1AGSK3BMEN1KMT2APOLB | |
| Hesperidin SCHEMBL18654117 | 1.00 | KDM1A (1.00) | KDM1AGSK3BMEN1KMT2APOLB | |
| Hesperidin SCHEMBL22946699 | 1.00 | KDM1A (1.00) | KDM1AGSK3BMEN1KMT2APOLB | |
| Hesperidin SCHEMBL94586 | 1.00 | KDM1A (1.00) | KDM1AGSK3BMEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230322838-A1 | DIOSMIN PREPARATION METHOD | LES LABORATOIRES SERVIER (FR) | 2023-10-12 | — | — | US | disclosed |
| US-20230322838-A1 | DIOSMIN PREPARATION METHOD | LES LABORATOIRES SERVIER (FR) | 2023-10-12 | — | — | US | disclosed |
| US-10711025-B2 | Process for the preparation of diosmin | INTERQUIM, S.A. (ES) | 2020-07-14 | — | — | US | disclosed |
| EP-3253772-B1 | PROCESS FOR THE PREPARATION OF DIOSMIN | INTERQUIM SA (ES) | 2020-04-22 | — | — | EP | disclosed |
| US-20190225639-A1 | PROCESS FOR THE PREPARATION OF DIOSMIN | INTERQUIM, S.A. (ES) | 2019-07-25 | — | — | US | disclosed |
| US-10287310-B2 | Process for the preparation of diosmin | INTERQUIM, S.A. (ES) | 2019-05-14 | — | — | US | disclosed |
| US-20180216152-A1 | METHOD FOR THE BIOTECHNOLOGICAL PRODUCTION OF FLAVONE GLYCOSIDE DIHYDROCHALCONES | SYMRISE AG (DE) | 2018-08-02 | — | — | US | disclosed |
| US-20180216152-A1 | METHOD FOR THE BIOTECHNOLOGICAL PRODUCTION OF FLAVONE GLYCOSIDE DIHYDROCHALCONES | SYMRISE AG (DE) | 2018-08-02 | — | — | US | disclosed |
| US-20180016292-A1 | PROCESS FOR THE PREPARATION OF DIOSMIN | INTERQUIM, S.A. (ES) | 2018-01-18 | — | — | US | disclosed |
| US-20180016292-A1 | PROCESS FOR THE PREPARATION OF DIOSMIN | INTERQUIM, S.A. (ES) | 2018-01-18 | — | — | US | disclosed |
| WO-2016124585-A1 | PROCESS FOR THE PREPARATION OF DIOSMIN | INTERQUIM, S.A. (ES) | 2016-08-11 | — | — | WO | disclosed |
| EP-3053930-A1 | Process for the preparation of diosmin | Interquim, S.A. (ES) | 2016-08-10 | — | — | EP | disclosed |
| EP-2120924-B1 | AN ANTI-DIABETIC EXTRACT OF HONEYBUSH | ZADEC APS (DK) | 2016-03-09 | — | — | EP | disclosed |
| US-20140154373-A1 | METHOD FOR POST-HARVEST TREATING CITRUS FRUIT | Masse en faillite Adamant Technologies SA par l'Office des Faillites (CH) | 2014-06-05 | — | — | US | disclosed |
| US-20140154373-A1 | METHOD FOR POST-HARVEST TREATING CITRUS FRUIT | Masse en faillite Adamant Technologies SA par l'Office des Faillites (CH) | 2014-06-05 | — | — | US | disclosed |
| US-20120251643-A1 | ANTI-DIABETIC EXTRACT OF HONEYBUSH | ZADEC APS (DK) | 2012-10-04 | — | — | US | disclosed |
| EP-2120924-A2 | AN ANTI-DIABETIC EXTRACT OF HONEYBUSH | Zadec APS (DK) | 2009-11-25 | — | — | EP | disclosed |
| WO-2008110552-A9 | AN ANTI-DIABETIC EXTRACT OF HONEYBUSH | ZADEC APS (DK) | 2008-12-04 | — | — | WO | disclosed |
| WO-2008110552-A2 | AN ANTI-DIABETIC EXTRACT OF HONEYBUSH | ZADEC APS (DK) | 2008-09-18 | — | — | WO | disclosed |
| US-20040038914-A1 | Flavone/ flavanone derivatives for the systemic treatment and prophlaxis of uv-induced dermatoses | KRUTMANN JEAN (DE) | 2004-02-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10711025-B2 | Process for the preparation of diosmin | DHPS, DBN1, AOC1 | KDM1A 3245/4885GSK3B 4010/4885MEN1 49/4885 |
| US-20180016292-A1 | PROCESS FOR THE PREPARATION OF DIOSMIN | DBN1, DHPS, QDPR | KDM1A 3197/4885GSK3B 3732/4885MEN1 39/4885 |
| US-20120251643-A1 | ANTI-DIABETIC EXTRACT OF HONEYBUSH | IAPP, DPP4, DPP3 | KDM1A 3222/4885GSK3B 1949/4885MEN1 3939/4885 |
| US-20040038914-A1 | Flavone/ flavanone derivatives for the systemic treatment and prophlaxis of uv-induced dermatoses | COLGALT1, PNN, F2 | KDM1A 581/4885GSK3B 2515/4885MEN1 2730/4885 |
| US-20190225639-A1 | PROCESS FOR THE PREPARATION OF DIOSMIN | DHPS, DBN1, AOC1 | KDM1A 3245/4885GSK3B 4010/4885MEN1 49/4885 |
| US-20230322838-A1 | DIOSMIN PREPARATION METHOD | DHPS, SI, SPAST | KDM1A 2171/4885GSK3B 737/4885MEN1 282/4885 |
| US-10287310-B2 | Process for the preparation of diosmin | DBN1, DHPS, QDPR | KDM1A 3197/4885GSK3B 3732/4885MEN1 39/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.