Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.47 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.44 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.43 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | GLS | O94925 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9118102 | 0.86 | HRH3 (0.49) | HRH3MTNR1AGABRA1GABRB2TP53 | |
| SCHEMBL3905377 | 0.85 | HRH3 (0.51) | HRH3MTNR1AGABRA1GABRB2TP53 | |
| SCHEMBL9628962 | 0.83 | HRH3 (0.55) | HRH3MTNR1AGABRA1GABRB2TP53 | |
| SCHEMBL10394809 | 0.81 | CYP19A1 (0.43) | MTNR1ATSHR | |
| SCHEMBL10257134 | 0.79 | HRH3 (0.60) | HRH3MTNR1AGABRA1GABRB2TP53 | |
| SCHEMBL9629907 | 0.78 | MTNR1A (0.52) | HRH3MTNR1AGABRA1GABRB2TP53 | |
| SCHEMBL5722693 | 0.77 | HRH3 (0.51) | HRH3MTNR1AGABRA1GABRB2TP53 | |
| SCHEMBL3915713 | 0.76 | TSHR (0.43) | HRH3MTNR1AGABRA1GABRB2TP53 | |
| SCHEMBL9118219 | 0.76 | HRH3 (0.46) | HRH3MTNR1AGABRA1GABRB2TP53 | |
| SCHEMBL9628115 | 0.75 | HRH3 (0.57) | HRH3MTNR1AGABRA1GABRB2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5204334-A | Inhibition of calcium resorption; osteoporosis; Paget's disease; bone disorders | CIBA-GEIGY CORPORATION (US) | 1993-04-20 | — | — | US | disclosed |