Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | TAS2R38 | P59533 | 3/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | TYR | P14679 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.40 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenyl Biguanide SCHEMBL467623 | 0.94 | ALDH1A1 (0.50) | ALDH1A1TAS2R38TP53TSHRHSD17B10 | |
| Phenyl Biguanide SCHEMBL2721730 | 0.92 | ALDH1A1 (0.48) | ALDH1A1TAS2R38TP53TSHRHSD17B10 | |
| Phenyl Biguanide SCHEMBL28093786 | 0.92 | ALDH1A1 (0.48) | ALDH1A1TAS2R38TP53TSHRHSD17B10 | |
| Phenyl Biguanide SCHEMBL1989457 | 0.90 | ALDH1A1 (0.47) | ALDH1A1TAS2R38TP53TSHRHSD17B10 | |
| Phenyl Biguanide SCHEMBL27966288 | 0.90 | POLB (0.42) | ALDH1A1TAS2R38TP53TSHRHSD17B10 | |
| Phenyl Biguanide SCHEMBL16702225 | 0.89 | GAA (0.48) | ALDH1A1TAS2R38TP53TSHRHSD17B10 | |
| Phenyl Biguanide SCHEMBL1592736 | 0.87 | MAPT (0.47) | ALDH1A1TAS2R38TP53TSHRHSD17B10 | |
| Phenyl Biguanide SCHEMBL27966486 | 0.85 | HSD17B10 (0.52) | ALDH1A1TAS2R38TP53TSHRHSD17B10 | |
| Phenyl Biguanide SCHEMBL28429189 | 0.85 | ACP1 (0.44) | ALDH1A1TAS2R38TP53TSHRHSD17B10 | |
| Phenyl Biguanide SCHEMBL28014085 | 0.85 | ALDH1A1 (0.43) | ALDH1A1TAS2R38TP53TSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0562668-A1 | Monirritating antitartar and antiplaque oral compositions | UNILEVER N.V. (NL) | 1993-09-29 | — | — | EP | disclosed |
| US-5192533-A | Hypophite-acrylic polymer | CHESEBROUGH-POND'S USA CO., DIVISION OF CONOPCO, INC. (US) | 1993-03-09 | — | — | US | disclosed |
| US-4886658-A | MIXTURE OF MONOPEROXYPHTHALATE AND BISGUANID COMPOUND | THE PROCTER & GAMBLE COMPANY (US) | 1989-12-12 | — | — | US | disclosed |
| US-4157387-A | Dentifrice composition containing an abrasive coated with a cationic water soluble polymer | THE PROCTER & GAMBLE COMPANY (US) | 1979-06-05 | — | — | US | disclosed |
| US-4110083-A | HARD MINERAL PARTICLES COATED WITH A CATIONIC WATER-SOLUBLE POLYMER | THE PROCTER & GAMBLE COMPANY (US) | 1978-08-29 | — | — | US | disclosed |
| US-4025616-A | Oral compositions for plaque, caries and calculus retardation with reduced staining tendencies | THE PROCTER & GAMBLE COMPANY (US) | 1977-05-24 | — | — | US | disclosed |
| US-3934002-A | BIS-GUANIDE | THE PROCTER & GAMBLE COMPANY (US) | 1976-01-20 | — | — | US | disclosed |