Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 3/20 | 0.53 |
| ▸ | HTR2B | P41595 | 1/20 | 0.53 |
| ▸ | HTR2A | P28223 | 3/20 | 0.49 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.48 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.48 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.48 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.45 |
| ▸ | HTR6 | P50406 | 5/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | NAMPT | P43490 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9460224 | 0.87 | HTR2C (0.50) | HTR2CHTR2BHTR2AABCC9ABCC8 | |
| SCHEMBL7182433 | 0.86 | HTR2A (0.60) | HTR2CHTR2BHTR2AABCC9ABCC8 | |
| SCHEMBL18187421 | 0.86 | ALDH1A1 (0.58) | ALDH1A1HTR6SMN1; SMN2MAPTLMNA | |
| SCHEMBL775608 | 0.86 | HTR2C (0.59) | HTR2CHTR2BHTR2AABCC9ABCC8 | |
| SCHEMBL777135 | 0.84 | HTR6 (0.61) | HTR2CHTR2BHTR2AABCC9ABCC8 | |
| SCHEMBL28582400 | 0.82 | ALDH1A1 (0.59) | HTR2CHTR2BALDH1A1HTR6SMN1; SMN2 | |
| SCHEMBL15239367 | 0.82 | ALDH1A1 (0.51) | ALDH1A1HTR6SMN1; SMN2MAPTLMNA | |
| SCHEMBL9459975 | 0.81 | EGFR (0.48) | HTR2CHTR2BHTR2AALDH1A1KCNH2 | |
| SCHEMBL24720985 | 0.81 | GAA (0.59) | HTR2CHTR2BHTR2AABCC9ABCC8 | |
| SCHEMBL3446114 | 0.81 | ALDH1A1 (0.59) | HTR2CHTR2BHTR2AABCC9ABCC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5185454-A | Reacting aryl bromide with acetylene in presence of palladium catalyst and nitrogen-containing heterocyclic base | BAYER AKTIENGESELLSCHAFT (DE) | 1993-02-09 | — | — | US | disclosed |