Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3913754 | 0.79 | ALDH1A1 (0.49) | ALDH1A1TSHRHPGDPOLBCYP2C19 | |
| SCHEMBL2064880 | 0.77 | ALDH1A1 (0.58) | ALDH1A1TSHRHPGDPOLBCYP2C19 | |
| SCHEMBL3698978 | 0.77 | ACHE (0.43) | ALDH1A1TSHRHPGDPOLBCYP2C19 | |
| SCHEMBL1507806 | 0.75 | POLB (0.47) | ALDH1A1TSHRHPGDPOLBCYP2C19 | |
| SCHEMBL24860297 | 0.75 | IDO1 (0.38) | ALDH1A1HPGD | |
| SCHEMBL3137939 | 0.75 | ALDH1A1 (0.51) | ALDH1A1TSHRHPGDPOLBCYP2C19 | |
| SCHEMBL5682058 | 0.75 | LMNA (0.42) | ALDH1A1 | |
| SCHEMBL1089020 | 0.75 | ALDH1A1 (0.51) | ALDH1A1TSHRHPGDACHE | |
| SCHEMBL1665924 | 0.74 | ALDH1A1 (0.55) | ALDH1A1TSHRHPGDPOLBCYP2C19 | |
| SCHEMBL9459074 | 0.74 | ALDH1A1 (0.55) | ALDH1A1TSHRHPGDPOLBCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5262333-A | Fluorescence polarization immunoassay | ABBOTT LABORATORIES (US) | 1993-11-16 | — | — | US | disclosed |
| EP-0371253-A2 | Method and reagents for detecting amphetamine and/or d-methamphetamine in biological samples | ABBOTT LABORATORIES (US) | 1990-06-06 | — | — | EP | disclosed |