Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | APP | P05067 | 3/20 | 0.52 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ACACB | O00763 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 2/20 | 0.38 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29018693 | 0.87 | L3MBTL1 (0.66) | LMNAL3MBTL1APPAOC3KCNH2 | |
| SCHEMBL7134534 | 0.82 | APP (0.64) | L3MBTL1APPKCNH2CA12CA1 | |
| SCHEMBL9460884 | 0.80 | LMNA (0.46) | LMNAL3MBTL1CA12CA1CA2 | |
| SCHEMBL2601884 | 0.78 | LMNA (0.57) | LMNAL3MBTL1APPALDH1A1NPC1 | |
| SCHEMBL3190454 | 0.77 | MAPT (0.47) | APPKCNH2MAPTALDH1A1NPC1 | |
| SCHEMBL18121550 | 0.77 | APP (0.84) | APPKCNH2CA12CA1CA2 | |
| SCHEMBL19934119 | 0.75 | APP (0.61) | L3MBTL1APPKCNH2CA12CA1 | |
| SCHEMBL14770101 | 0.75 | APP (0.55) | LMNAL3MBTL1APPKCNH2CA12 | |
| SCHEMBL28151462 | 0.75 | APP (0.55) | L3MBTL1APPKCNH2CA12CA1 | |
| SCHEMBL10300057 | 0.73 | APP (0.77) | L3MBTL1APPKCNH2CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0383621-B1 | Diphenyldiacetylene derivative | TODA KOGYO CORP (JP) | 1993-12-08 | — | — | EP | disclosed |
| US-5196586-A | Polydiphenyldiacetylenes | TODA KOGYO CORP. (JP) | 1993-03-23 | — | — | US | disclosed |
| EP-0383621-A1 | Diphenyldiacetylene derivative | TODA KOGYO CORP. (JP) | 1990-08-22 | — | — | EP | disclosed |