Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.36 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.36 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.36 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.36 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.36 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.33 |
| ▸ | MAP3K14 | Q99558 | 2/20 | 0.32 |
| ▸ | APP | P05067 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.31 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.31 |
| ▸ | GRM5 | P41594 | 1/20 | 0.31 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.31 |
| ▸ | KDR | P35968 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2889973 | 0.89 | EGFR (0.49) | EGFRASIC3PDK1PDK2PDK3 | |
| SCHEMBL31536232 | 0.89 | EGFR (0.49) | EGFRASIC3PDK1PDK2PDK3 | |
| SCHEMBL2892638 | 0.78 | HRH3 (0.44) | EGFRASIC3PDK1PDK2PDK3 | |
| SCHEMBL3190454 | 0.76 | MAPT (0.47) | ASIC3APP | |
| SCHEMBL9460884 | 0.75 | LMNA (0.46) | HAO1GRM5LMNA | |
| SCHEMBL9460886 | 0.75 | TSHR (0.37) | EGFRPTPN11APPTSHRGRM5 | |
| SCHEMBL15196555 | 0.74 | EGFR (0.48) | EGFRASIC3PDK1PDK2PDK3 | |
| SCHEMBL9460718 | 0.74 | IDH2 (0.40) | GRM5 | |
| SCHEMBL2884609 | 0.72 | TSHR (0.41) | EGFRPTPN11HAO1APPTSHR | |
| SCHEMBL11443850 | 0.72 | HAO1 (0.46) | EGFRASIC3HAO1MAP3K14TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0383621-B1 | Diphenyldiacetylene derivative | TODA KOGYO CORP (JP) | 1993-12-08 | — | — | EP | disclosed |
| US-5196586-A | Polydiphenyldiacetylenes | TODA KOGYO CORP. (JP) | 1993-03-23 | — | — | US | disclosed |
| EP-0383621-A1 | Diphenyldiacetylene derivative | TODA KOGYO CORP. (JP) | 1990-08-22 | — | — | EP | disclosed |