Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.33 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | TERT | O14746 | 1/20 | 0.30 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.30 |
| ▸ | PLK1 | P53350 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9460486 | 0.88 | NPC1 (0.38) | NPC1RAB9AHSD17B10POLBAMY1A | |
| SCHEMBL7081279 | 0.78 | SMN1; SMN2 (0.38) | NPC1RAB9AALDH1A1HSD17B10POLB | |
| SCHEMBL9460734 | 0.77 | NPC1 (0.35) | NPC1RAB9AKDM4EALDH1A1HPGD | |
| SCHEMBL3279686 | 0.75 | ALDH1A1 (0.33) | NPC1RAB9AKDM4EALDH1A1HPGD | |
| SCHEMBL3280651 | 0.72 | ALDH1A1 (0.34) | NPC1RAB9AKDM4EALDH1A1HPGD | |
| SCHEMBL3279274 | 0.71 | ALDH1A1 (0.55) | NPC1RAB9AKDM4EALDH1A1HPGD | |
| SCHEMBL15910157 | 0.70 | NPC1 (0.55) | NPC1RAB9ARXFP1KDM4EALDH1A1 | |
| SCHEMBL9460562 | 0.69 | CNR1 (0.36) | KDM4EALDH1A1HPGDHSD17B10CNR2 | |
| SCHEMBL11728530 | 0.69 | SMN1; SMN2 (0.38) | NPC1RAB9AALDH1A1HSD17B10POLB | |
| SCHEMBL9178179 | 0.69 | HSP90AA1 (0.32) | CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5262541-A | Reaction with sugar as a reducing agent | FAIRMONT CHEMICAL COMPANY, INC. (US) | 1993-11-16 | — | — | US | disclosed |
| US-4780541-A | Method for preparing 2-phenylbenzotriazoles and 2-phenylbenzotriazole-N-oxides | CHEMIPRO KASEI KAISHA, LTD. (JP) | 1988-10-25 | — | — | US | disclosed |