Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.31 |
| ▸ | BCHE | P06276 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9460732 | 0.88 | NPC1 (0.36) | NPC1RAB9APOLBAMY1ACNR2 | |
| SCHEMBL9178544 | 0.78 | SMN1; SMN2 (0.41) | NPC1RAB9APOLBLMNACA2 | |
| SCHEMBL7081592 | 0.75 | NPC1 (0.56) | NPC1RAB9APOLBLMNASMN1; SMN2 | |
| SCHEMBL9179117 | 0.74 | NPC1 (0.42) | NPC1RAB9APOLBLMNATSHR | |
| SCHEMBL14997992 | 0.72 | NPC1 (0.56) | NPC1RAB9APOLBAMY1ALMNA | |
| SCHEMBL11820175 | 0.72 | AMY1A (0.58) | AMY1ACNR2GPR55CA12CA1 | |
| SCHEMBL3027866 | 0.72 | AMY1A (0.58) | AMY1ACNR2GPR55CA12CA1 | |
| SCHEMBL31267541 | 0.72 | NPC1 (0.66) | NPC1RAB9APOLBAMY1ALMNA | |
| SCHEMBL258759 | 0.72 | NPC1 (0.66) | NPC1RAB9APOLBAMY1ALMNA | |
| SCHEMBL29494818 | 0.72 | NPC1 (0.66) | NPC1RAB9APOLBAMY1ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5262541-A | Reaction with sugar as a reducing agent | FAIRMONT CHEMICAL COMPANY, INC. (US) | 1993-11-16 | — | — | US | disclosed |
| EP-0257151-B1 | METHOD FOR PREPARING 2-PHENYLBENZOTRIAZOLES AND 2-PHENYLBENZOTRIAZOLE-N-OXIDES | CHEMIPRO KASEI KAISHA, LTD. (JP) | 1992-01-29 | — | — | EP | disclosed |
| US-4943637-A | Method for preparing 2-phenylbenzotriazoles | CHEMIPRO KASEI KAISHA, LTD. (JP) | 1990-07-24 | — | — | US | disclosed |
| US-4835284-A | Method for preparing 2-phenylbenzotriazoles and 2-phenylbenzotriazole-N-oxides | CHEMIPRO KASEI KAISHA, LTD. (JP) | 1989-05-30 | — | — | US | disclosed |
| US-4780541-A | Method for preparing 2-phenylbenzotriazoles and 2-phenylbenzotriazole-N-oxides | CHEMIPRO KASEI KAISHA, LTD. (JP) | 1988-10-25 | — | — | US | disclosed |