Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.55 |
| ▸ | TGM2 | P21980 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.53 |
| ▸ | MEN1 | O00255 | 5/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.52 |
| ▸ | GAA | P10253 | 6/20 | 0.52 |
| ▸ | POLB | P06746 | 3/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | MYOC | Q99972 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9567011 | 0.87 | MEN1 (0.67) | MAPTTGM2KMT2AMEN1ALDH1A1 | |
| SCHEMBL9461875 | 0.84 | MAPT (0.54) | MAPTKMT2AMEN1ALDH1A1GAA | |
| SCHEMBL11768574 | 0.80 | MEN1 (0.58) | MAPTTGM2KMT2AMEN1ALDH1A1 | |
| SCHEMBL11772507 | 0.80 | KMT2A (0.60) | MAPTTGM2KMT2AMEN1POLB | |
| SCHEMBL11839996 | 0.80 | MEN1 (0.72) | MAPTTGM2KMT2AMEN1ALDH1A1 | |
| SCHEMBL9461985 | 0.79 | NPSR1 (0.56) | MAPTTGM2ALDH1A1GAAPOLB | |
| SCHEMBL9461873 | 0.79 | PTGS2 (0.49) | ALDH1A1GAAPOLBTDP1HTT | |
| SCHEMBL9461416 | 0.79 | SMN1; SMN2 (0.51) | MAPTTGM2KMT2AMEN1ALDH1A1 | |
| SCHEMBL9461431 | 0.79 | TGM2 (0.49) | MAPTTGM2KMT2AMEN1ALDH1A1 | |
| SCHEMBL9461426 | 0.79 | POLB (0.49) | MAPTTGM2KMT2AALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0542084-A1 | Use of inhibitors of color generation in chromogenic assays | Bayer Corporation (US) | 1993-05-19 | — | — | EP | disclosed |
| US-5212066-A | Semicarbazide, thiosemicarbazide and carbazide as inhibiitors of color generation | MILES INC. (US) | 1993-05-18 | — | — | US | disclosed |