Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | POLB | P06746 | 3/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | DDX3X | O00571 | 1/20 | 0.54 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA5A | P35218 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.46 |
| ▸ | BAZ1A | Q9NRL2 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9461541 | 0.84 | MAPT (0.55) | MAPTMEN1KMT2APOLBHTT | |
| SCHEMBL31064998 | 0.80 | KMT2A (0.56) | MAPTMEN1KMT2APOLBHTT | |
| SCHEMBL9448739 | 0.79 | MAPT (0.54) | MAPTMEN1KMT2APOLBHTT | |
| SCHEMBL9462096 | 0.79 | TGM2 (0.50) | MEN1KMT2APOLBHTTSMN1; SMN2 | |
| SCHEMBL9461426 | 0.77 | POLB (0.49) | MAPTKMT2APOLBSMN1; SMN2ALDH1A1 | |
| SCHEMBL20984089 | 0.77 | KMT2A (0.65) | MAPTMEN1KMT2APOLBHTT | |
| SCHEMBL10433499 | 0.76 | MEN1 (0.63) | MAPTMEN1KMT2APOLBHTT | |
| SCHEMBL6570860 | 0.76 | KMT2A (0.62) | MAPTMEN1KMT2APOLBHTT | |
| SCHEMBL11764491 | 0.75 | MAPT (0.52) | MAPTSMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL8599639 | 0.75 | KMT2A (0.61) | MAPTMEN1KMT2APOLBHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0542084-A1 | Use of inhibitors of color generation in chromogenic assays | Bayer Corporation (US) | 1993-05-19 | — | — | EP | claimed |
| US-5212066-A | Semicarbazide, thiosemicarbazide and carbazide as inhibiitors of color generation | MILES INC. (US) | 1993-05-18 | — | — | US | claimed |