Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | PLEC | Q15149 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | PIM1 | P11309 | 1/20 | 0.37 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9463137 | 0.90 | LMNA (0.50) | LMNASMN1; SMN2GAAKDM4EL3MBTL1 | |
| SCHEMBL13299569 | 0.90 | LMNA (0.50) | LMNASMN1; SMN2GAAKDM4EL3MBTL1 | |
| SCHEMBL3126497 | 0.80 | DYRK1A (0.50) | LMNASMN1; SMN2MAPTPOLBALDH1A1 | |
| SCHEMBL3126492 | 0.80 | DYRK1A (0.50) | LMNASMN1; SMN2MAPTPOLBALDH1A1 | |
| SCHEMBL21546299 | 0.76 | LMNA (0.39) | LMNASMN1; SMN2GAAKDM4EL3MBTL1 | |
| SCHEMBL9488911 | 0.71 | NR5A1 (0.47) | LMNASMN1; SMN2KDM4EMEN1KMT2A | |
| SCHEMBL28502895 | 0.70 | ALDH1A1 (0.49) | LMNASMN1; SMN2KDM4EL3MBTL1MAPT | |
| SCHEMBL1822537 | 0.69 | MAPT (0.36) | LMNASMN1; SMN2KDM4EMEN1KMT2A | |
| SCHEMBL1822536 | 0.69 | MAPT (0.36) | LMNASMN1; SMN2KDM4EMEN1KMT2A | |
| SCHEMBL18722755 | 0.69 | LMNA (0.47) | LMNASMN1; SMN2GAAKDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0368717-B1 | 5-BENZYLIDENE 3-OXA CYCLOPENTANONE DERIVATIVES, PROCESS FOR THEIR MANUFACTURE AND THEIR USE IN COSMETIC COMPOSITIONS TO PROTECT THE SKIN AND THE HAIR AGAINST SUN RADIATION | L'OREAL (FR) | 1993-01-20 | — | — | EP | claimed |
| JP-2172983-A | — | — | None | — | — | JP | disclosed |
| US-5217709-A | SUNSCREENING COMPOSITIONS CONTAINING 5-BENZYLIDENE-3-OXACYCLOPENTANONE | L'OREAL (FR) | 1993-06-08 | — | — | US | disclosed |
| EP-0368717-B1 | 5-BENZYLIDENE 3-OXA CYCLOPENTANONE DERIVATIVES, PROCESS FOR THEIR MANUFACTURE AND THEIR USE IN COSMETIC COMPOSITIONS TO PROTECT THE SKIN AND THE HAIR AGAINST SUN RADIATION | L'OREAL (FR) | 1993-01-20 | — | — | EP | disclosed |
| JP-H02172983-A | 5-BENZYLIDENE-3-OXACYLOPENTANONE DERIVATIVE AND COSMETIC COMPOSITION | L'OREAL SA | 1990-07-04 | — | — | JP | disclosed |
| EP-0368717-A1 | 5-Benzylidene 3-oxa cyclopentanone derivatives, process for their manufacture and their use in cosmetic compositions to protect the skin and the hair against sun radiation | L'OREAL (FR) | 1990-05-16 | — | — | EP | disclosed |